SML3243

NA-11

≥98% (HPLC)

• 別名: N-(2-(2-(5-hydroxypent-1-yn-1-yl)phenyl)-4H,10H-benzo[f]pyrazolo[5,1-c][1,4]oxazepin-7-yl)acetamide
• 実験式（ヒル表記法）: C₂₄H₂₃N₃O₃
• 分子量: 401.46
• UNSPSCコード: 12352107
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 色: white to beige
• 溶解性: DMSO: 2 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: OCCCC#CC1=CC=CC=C1C2=NN3C(COC(C=C(NC(C)=O)C=C4)=C4C3)=C2

詳細

生物化学的／生理学的作用

NA-11 is a potent and selective activator of PFKL (phosphofructokinase-1 liver type) that suppress excessive NOX2-dependent oxidative burst and neutrophil cell death (NETosis). NA-11 decreases neutrophiles efficiency to kill bacteria. It prevents neutrophil-induced tissue damage.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3