SML3158

6-Methylflavone

≥98% (HPLC)

• 別名: 6-Methyl-2-phenyl-4H-1-benzopyran-4-one, 6-Methyl-2-phenyl-4H-chromen-4-one
• 実験式（ヒル表記法）: C₁₆H₁₂O₂
• CAS番号: 29976-75-8
• 分子量: 236.27
• MDL番号: MFCD00017461
• UNSPSCコード: 51111800
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 色: white to beige
• mp: 119-122 °C (dec.) (lit.)
• 溶解性: DMSO: 2 mg/mL, clear (warmed)
• 保管温度: 2-8°C
• SMILES記法: Cc1ccc2OC(=CC(=O)c2c1)c3ccccc3
• InChI: 1S/C16H12O2/c1-11-7-8-15-13(9-11)14(17)10-16(18-15)12-5-3-2-4-6-12/h2-10H,1H3
• InChI Key: NOQJBXPAMJLUSS-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

6-Methylflavone is a bitter taste blocker that significantly reduces bitter test of HIV drug tenofovir alafenamide in human subjects. 6-Methylflavone is a selective and potent modulator of TAS2R39 bitter test receptor that blocks it response to tenofovir alafenamide. 6-Methylflavone is a positive allosteric modulator (PAM) of α1β2γ2L and α1β2 GABAA receptors.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable