SML0283

Amorolfine hydrochloride

≥98% (HPLC)

• 別名: (2R,6S)-rel-4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine hydrochloride, Ro 14-4767/002
• 実験式（ヒル表記法）: C₂₁H₃₅ON · HCl
• CAS番号: 78613-38-4
• 分子量: 353.97
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825291
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 保管条件: desiccated
• 色: white to beige
• 溶解性: DMSO: ≥5 mg/mL (warmed)
• 保管温度: room temp
• SMILES記法: Cl.CCC(C)(C)c1ccc(CC(C)CN2C[C@H](C)O[C@H](C)C2)cc1
• InChI: 1S/C21H35NO.ClH/c1-7-21(5,6)20-10-8-19(9-11-20)12-16(2)13-22-14-17(3)23-18(4)15-22;/h8-11,16-18H,7,12-15H2,1-6H3;1H/t16?,17-,18+;
• InChI Key: XZKWIPVTHGWDCF-KUZYQSSXSA-N

詳細

アプリケーション

Amorolfine hydrochloride has been used as an antifungal agent.

生物化学的／生理学的作用

Amorolfine blocks ergosterol biosynthesis by interfering with delta 14 reduction and the delta 7-8 isomerisation.

Amorolfine hydrochloride is a potential for treating onychomycosis infected nails by topical application. A 5% solution combination with fluconazole is effective on sensitive fungus in fingernail onychomycosis.

Amorolfine is a broad-based antifungal agent with fungicidal effects against most fungi, dermatophytes and yeasts.

安全性情報

• ピクトグラム: GHS07,GHS09
• シグナルワード: Warning
• 危険有害性情報: H302,H315,H411
• 注意書き: P264 - P273 - P280 - P301 + P312 - P302 + P352 - P332 + P313
• 危険有害性の分類: Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Irrit. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable