SAB5700521

Anti-Phospho-PERK-T982 antibody produced in rabbit

• 別名: EIF2AK3, PEK, PERK, WRS
• UNSPSCコード: 12352203

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: 125
• 化学種の反応性: mouse, human, rat
• 濃度: 1.67 mg/ml
• テクニック: western blot: 1:500-1:2000
• UniProtアクセッション番号: Q9NZJ5
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pThr982)
• 遺伝子情報: human ... EIF2AK3(9451)

詳細

詳細

The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.

免疫原

A phospho specific peptide corresponding to residues surrounding T980 of human PERK.

物理的形状

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

保管および安定性

Store at -20℃. Avoid freeze / thaw cycles.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable