SMB00577

Diallyl trisulfide

≥97% (HPLC)

• 別名: Allyl trisulfide, Di-2-propenyl trisulfide
• 実験式（ヒル表記法）: C₆H₁₀S₃
• CAS番号: 2050-87-5
• 分子量: 178.34
• EC Number: 218-107-8
• MDL番号: MFCD00040025
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825066
• NACRES: NA.25

特性

• 由来生物: Allium sativum L.
• 品質水準: 200
• アッセイ: ≥97% (HPLC)
• フォーム: liquid
• アプリケーション: metabolomics; vitamins, nutraceuticals, and natural products
• 保管温度: −20°C
• SMILES記法: C=CCSSSCC=C
• InChI: 1S/C6H10S3/c1-3-5-7-9-8-6-4-2/h3-4H,1-2,5-6H2
• InChI Key: UBAXRAHSPKWNCX-UHFFFAOYSA-N

詳細

詳細

Diallyl trisulfide (DATS) is one of the stable naturally occurring bioactive polysulfide compounds found in Allium vegetables, especially in garlic.

アプリケーション

Diallyl trisulfide (DATS) has been used as an exogenous hydrogen sulfide (H₂S)donor to study the effects on proliferation, apoptosis, and autophagy of human urothelial carcinoma (UC) cells in vitro.

生物化学的／生理学的作用

Diallyl trisulfide elicits cardioprotective and anti-metabolic syndrome (MetS) effects against ex vivo induced myocardial ischemia/reperfusion (I/R) injury in MetS rats (male Wistar albino). It is a potent anti-cancer agent and acts by modulating different cancer-related pathways, inducing cell cycle arrest, apoptosis, metastasis, and angiogenesis in in vitro studies. DATS is also an effective therapeutic agent against multidrug resistance in triple-negative breast cancer (TNBC). DATS and its nanoemulsions display high antifungal activity against wood-rotting fungi such as T. hirsuta and L. sulphureus. It also provides protection against brain damage induced by ischemia/reperfusion (I/R) by activating nuclear factor erythroid 2-related factor 2 (Nrf2) in rat brains.

安全性情報

• ピクトグラム: GHS06
• シグナルワード: Danger
• 危険有害性情報: H301
• 注意書き: P264 - P270 - P301 + P310 - P405 - P501
• 危険有害性の分類: Acute Tox. 3 Oral
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable