SAB5900404

Anti-Monkeypox virus/MPXV E8L Antibody (SAA0285)

• 別名: E8L, Cell surface-binding protein, Carbonic anhydrase homolog, Monkeypox virus (MPXV)
• UNSPSCコード: 12352203

特性

• 由来生物: mouse
• 品質水準: 100
• リコンビナント: expressed in CHO cells
• 結合体: unconjugated
• 抗体製品の状態: affinity purified immunoglobulin
• クローン: SAA0285, recombinant monoclonal
• アッセイ: >95% (SDS-PAGE)
• 形状: liquid
• 分子量: 150 kDa
• 化学種の反応性: monkeypox virus
• 濃度: 1 mg/mL
• テクニック: ELISA: 1:2000-1:4000; neutralization: 0.01-10 μg/mL
• 色: colorless
• pH: 7.4
• アイソタイプ: IgG2a, kappa
• タンパク質IDアクセッション番号: NP_536532.1
• UniProtアクセッション番号: Q8V4Y0
• 輸送温度: wet ice
• 保管温度: -65 to -96°C
• ターゲットの翻訳後修飾: unmodified

詳細

詳細

Anti-Monkeypox virus/MPXV E8L Antibody, clone SAA0285, is a hybrid protein of mouse and human origin, consisting of a single light chain and a single heavy chain. The light chain is composed of a variable region (VL) and a constant region (CL) while the heavy chain is composed of a variable region (VH) and a constant region (CH). The VL and VH regions are responsible for the binding of the antibody to the antigens on the Monkeypox virus, while the CL and CH regions are responsible for the production of anti-viral proteins.
Monkeypox virus (MPXV), like smallpox virus, belongs to the genus Orthopoxvirus. Its morphology is consistent with that of orthopoxvirus, with a brick-shaped or oval shape with rounded corners and a size of 200~400nm. Brick-shaped or oval-shaped, covered by a lipoprotein membrane or envelope, with two protein-containing side bodies in the middle, and a thick membrane core containing a large double-stranded DNA gene body. The genome of Mpox virus is a double-stranded DNA, about 197kb long, and the end of the genome contains an identical but opposite terminal inverted repeat sequence. The virus contains 190 open reading frames, 4 of which are located in terminal inverted repeats. The core proteins of monkeypox virus are A29L, A35R, B6R, M1R, H3L.

特異性

Monoclonal Anti-Monkeypox virus/MPXV E8L Antibody, clone SAA0285 binds to the antigens on the surface of the Monkeypox virus, blocking the virus from entering host cells. It also activates the production of anti-viral proteins, which neutralize the virus and inhibit its replication. The antibody also activates the immune system, helping to clear the virus from the body.

アプリケーション

ELISA,neutralization

包装

100µg per vial / 1 mg per vial

保管および安定性

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable