PRS3197

Anti-Caspase-12 (small) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 別名: Anti-Caspase 12
• MDL番号: MFCD03454855
• UNSPSCコード: 12352203
• NACRES: NA.41
• 結合体: unconjugated
• application: ELISA (i); IHC; WB
• クローン: polyclonal
• 化学種の反応性: mouse, human, rat
• citations: 5
• テクニック: immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: predicted mol wt 46 kDa
• 化学種の反応性: mouse, human, rat
• テクニック: immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProtアクセッション番号: O08736
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: mouse ... Casp12(12364)

詳細

詳細

Caspase-12 (CASP12) is an immunomodulatory factor, that is present in the cytoplasmic side of the ER (endoplasmic reticulum). It is upregulated highly in muscle, liver and kidney.

免疫原

a synthetic peptide corresponding to amino acids within the small cleavage product of murine caspase-12.

生物化学的／生理学的作用

Caspase-12 (CASP12) plays an important role in endoplasmic reticulum (ER)-related apoptosis. It moderates hepatocyte apoptosis prompted by carbon tetrachloride. Lack of caspase-12 (CASP12) increases cytokine responses.

関連事項

The action of this antibody can be blocked using blocking peptide SBP3197.

物理的形状

PBS溶液(0.02%アジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable