MAK192

Cholesterol Efflux Assay Kit

Sufficient for 100 Fluorometric tests

• UNSPSCコード: 12161503

特性

• アプリケーション: cosmetics; food and beverages; pharmaceutical
• 検出方法: fluorometric
• 関連疾患: cardiovascular diseases
• 保管温度: −20°C

詳細

詳細

Reverse Cholesterol Transport (RCT) is the mechanism by which the peripheral lipid burden is reduced by transport to liver and its fecal excretion. The first important step in RCT is the cholesterol efflux from macrophage-derived foam cells present in atherosclerotic plaques. The cholesterol efflux is critical for the maintenance of net cholesterol balance in arterial walls and in the reduction of proinflammatory responses triggered by lipid-laden macrophages.

アプリケーション

Cholesterol Efflux Assay Kit has been used in cholesterol efflux assay.

特徴および利点

Compatible with high-throughput handling systems.

適合性

Suitable for the determination of cholesterol efflux in cells.

原理

The Cholesterol Efflux Assay Kit is a high-throughput screening assay that measures cholesterol efflux in cells using fluorescent-labeled cholesterol (λ_Ex = 482 nm/ λ_Em = 515 nm). It is suitable for serum, isolated, or recombinant lipoprotein samples. It may also be used to screen small molecules for their effect on cholesterol efflux and therefore, may be a valuable tool in drug discovery programs.

キットの構成要素のみ

• Labeling Reagent
• Equilibration Buffer
• Reagent A
• Reagent B
• Cell Lysis Buffer
• Positive Control
• Serum Treatment Reagent

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H319
• 注意書き: P264 - P280 - P305 + P351 + P338 - P337 + P313
• 危険有害性の分類: Eye Irrit. 2
• 保管分類コード: 10 - Combustible liquids
• 引火点(°F): 188.6 °F - closed cup
• 引火点(℃): 87 °C - closed cup