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About This Item
実験式（ヒル表記法）:
C19H19NOS · C4H4O4
CAS番号:
分子量:
425.50
EC Number:
MDL番号:
UNSPSCコード:
12352200
PubChem Substance ID:
NACRES:
NA.77
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製品名
ケトチフェン フマル酸塩,
フォーム
powder
品質水準
オーガナイザー
Novartis
SMILES記法
OC(=O)\C=C\C(O)=O.CN1CCC(\CC1)=C2/c3ccccc3CC(=O)c4sccc24
InChI
1S/C19H19NOS.C4H4O4/c1-20-9-6-13(7-10-20)18-15-5-3-2-4-14(15)12-17(21)19-16(18)8-11-22-19;5-3(6)1-2-4(7)8/h2-5,8,11H,6-7,9-10,12H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
InChI Key
YNQQEYBLVYAWNX-WLHGVMLRSA-N
遺伝子情報
human ... HRH1(3269) , PDE7B(27115)
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関連するカテゴリー
詳細
Ketotifen fumarate salt is an antihistamine drug.
アプリケーション
Ketotifen fumarate salt has been used: for mast cell product antagonism, as a positive control in β-hexosaminidase release assay, as mast cell stabilizer to treat pregnant dams added to ad libitum drinking water
生物化学的／生理学的作用
H1 histamine receptor antagonist.
Ketotifen fumarate plays a key role in preventing histamine release by blocking the histamine H1 receptors. It interferes with the release of histamine, serotonin and other inflammatory mediators from mast cells. It exhibits with anti-allergic activity, anti-inflammatory effects including mast cell stabilization. It has been widely used for ophthalmic allergic conjunctivitis.
特徴および利点
This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
シグナルワード
Warning
危険有害性情報
危険有害性の分類
Acute Tox. 4 Oral - Eye Irrit. 2
保管分類コード
11 - Combustible Solids
WGK
WGK 3
個人用保護具 (PPE)
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
K2628-BULK:
K2628-1G:
K2628-VAR:
K2628-100MG:
K2628-500MG:
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