I1637

臭化イプラトロピウム 一水和物

≥98% (TLC), powder

• 別名: アトロピンイソプロピルブロミド
• 実験式（ヒル表記法）: C₂₀H₃₀BrNO₃ · H₂O
• CAS番号: 66985-17-9
• 分子量: 430.38
• EC Number: 244-873-8
• MDL番号: MFCD00792907
• UNSPSCコード: 12352200
• PubChem Substance ID: 24277843
• NACRES: NA.77

特性

• アッセイ: ≥98% (TLC)
• 形状: powder
• 色: white
• 溶解性: H₂O: 10 mg/mL
• オーガナイザー: Boehringer Ingelheim
• SMILES記法: O.[Br-].CC(C)[N@+]1(C)[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3
• InChI: 1S/C20H30NO3.BrH.H2O/c1-14(2)21(3)16-9-10-17(21)12-18(11-16)24-20(23)19(13-22)15-7-5-4-6-8-15;;/h4-8,14,16-19,22H,9-13H2,1-3H3;1H;1H2/q+1;;/p-1/t16-,17+,18+,19?,21?;;
• InChI Key: KEWHKYJURDBRMN-XSAPEOHZSA-M
• 遺伝子情報: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131) , CHRM4(1132) , CHRM5(1133)

詳細

アプリケーション

Ipratropium bromide monohydrate has been used for the inhibition of peripheral muscarinic receptors in rats.

生物化学的／生理学的作用

Ipratropium bromide monohydrate is a nonselective muscarinic acetylcholine receptor antagonist and a bronchodilator. In nebulized form, it is used for treating asthma and obstructive pulmonary diseases. It acts as a β₂ adrenoreceptor agonist. Ipratropium bromide monohydrate is an anticholinergic agent and competes with acetylcholine. It promotes bronchodilation by stimulating sympathetic pathways.

特徴および利点

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

その他情報

アトロピンのN-イソプロピル4級塩です。

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302 + H332,H319
• 注意書き: P261 - P264 - P271 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2