G5798

[10]-ジンゲロール

≥98% (HPLC)

• 別名: (S)-5-ヒドロキシ-1-(4-ヒドロキシ-3-メトキシフェニル)-3-テトラデカノン, 10-ジンゲロール
• 実験式（ヒル表記法）: C₂₁H₃₄O₄
• CAS番号: 23513-15-7
• 分子量: 350.49
• MDL番号: MFCD01682694
• UNSPSCコード: 85151701
• PubChem Substance ID: 329799946
• NACRES: NA.25

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• アプリケーション: metabolomics; vitamins, nutraceuticals, and natural products
• 保管温度: −20°C
• SMILES記法: CCCCCCCCC[C@H](O)CC(=O)CCc1ccc(O)c(OC)c1
• InChI: 1S/C21H34O4/c1-3-4-5-6-7-8-9-10-18(22)16-19(23)13-11-17-12-14-20(24)21(15-17)25-2/h12,14-15,18,22,24H,3-11,13,16H2,1-2H3/t18-/m0/s1
• InChI Key: AIULWNKTYPZYAN-SFHVURJKSA-N

詳細

詳細

[10]-Gingerol is a pungent, non-volatile phenolic compound of fresh ginger root.

アプリケーション

[10]-Gingerol has been used as an antibacterial agent to study its effects on Escherichia coli ATP synthase. It has also been used as an anti-hyperglycemic agent to test its effects on promoting glucose utilization in 3T3-L1 adipocytes and C2C12 myotubes.

生物化学的／生理学的作用

[10]-Gingerol is a potent anti-cancer agent and a known inhibitor of breast cancer cells growth by blocking cell proliferation and inducing programmed cell death. It also inhibits ovarian cancer cells growth by inducing G2 phase cell cycle arrest. 10-Gingerol elicits inhibitory effects towards triple breast cancer cells in both mouse models and in vitro studies. It also displays anti-neuroinflammatory and anti-hyperglycemic activities.

［10］-ジンゲロールは、ショウガ（Zingiber officinale）に含まれる生物活性化合物であり、抗炎症作用と抗酸化作用を示します。

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): 331.3 °F - closed cup
• 引火点(℃): 166.3 °C - closed cup