F9932

FFN511 trifluoroacetate salt hydrate

≥98% (HPLC)

• 別名: 8-(2-Amino-ethyl)-2,3,5,6-tetrahydro-1H,4H-11-oxa-3a-aza-benzo[de]anthracen-10-one trifluoroacetate salt hydrate, 9-(2-aminoethyl)-2,3,6,7-tetrahydro-1H,5H,11H-[1]benzopyrano[6,7,8-ij]quinolizin-11-one trifluoroacetate salt hydrate
• 実験式（ヒル表記法）: C₁₇H₂₀N₂O₂ · F₃CCO₂H · xH₂O
• CAS番号: 1004548-96-2
• 分子量: 398.38 (anhydrous basis)
• MDL番号: MFCD18632543
• UNSPSCコード: 12352200
• PubChem Substance ID: 329799792
• NACRES: NA.77

特性

• アッセイ: ≥98% (HPLC)
• 形状: powder
• 保管条件: desiccated
• 色: yellow
• 溶解性: DMSO: ≥20 mg/mL
• 保管温度: 2-8°C
• SMILES記法: O.OC(=O)C(F)(F)F.NCCC1=CC(=O)Oc2c3CCCN4CCCc(cc12)c34
• InChI: 1S/C17H20N2O2.C2HF3O2.H2O/c18-6-5-11-10-15(20)21-17-13-4-2-8-19-7-1-3-12(16(13)19)9-14(11)17;3-2(4,5)1(6)7;/h9-10H,1-8,18H2;(H,6,7);1H2
• InChI Key: RRBOSSKRCWVUPA-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

FFN511 is a fluorescent substrate for the synaptic vesicle monoamine transporters. FFN511 is used as an optical tracer of dopamine, a fluorescent false neurotransmitter (FFN) to visualize dopamine release from individual presynaptic terminals using time-lapse microscopsy fluorescence. The probe is sufficiently fluorescent so as to provide resolution of individual dopamine terminals at concentrations that do not interfere with normal catecholamine accumulation and transmission. FFN511 is compatible with GFPbased tags, the FM1-43 endocytic marker (Synapto Green), and other optical probes.

特徴および利点

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable