D1285

2′,3′-ジデオキシアデノシン

≥97% (HPLC)

• 別名: ddA
• 実験式（ヒル表記法）: C₁₀H₁₃N₅O₂
• CAS番号: 4097-22-7
• 分子量: 235.24
• Beilstein: 619924
• EC Number: 223-853-2
• MDL番号: MFCD00010534
• UNSPSCコード: 41106305
• PubChem Substance ID: 24893397
• NACRES: NA.51

特性

• アッセイ: ≥97% (HPLC)
• 形状: powder
• 光学活性: [α]/D -28.0±1.0
• mp: 181-184 °C (lit.)
• 溶解性: water: 100 mg/mL, clear, colorless
• 保管温度: 2-8°C
• SMILES記法: Nc1ncnc2n(cnc12)[C@H]3CC[C@@H](CO)O3
• InChI: 1S/C10H13N5O2/c11-9-8-10(13-4-12-9)15(5-14-8)7-2-1-6(3-16)17-7/h4-7,16H,1-3H2,(H2,11,12,13)/t6-,7+/m0/s1
• InChI Key: WVXRAFOPTSTNLL-NKWVEPMBSA-N
• 遺伝子情報: human ... DCK(1633)

詳細

詳細

2′,3′-Dideoxyadenosine is a nucleoside analog of deoxyadenosine. On deamination, it is converted to dideoxyinosine. It inhibits adenylyl cyclase and may play a key role in the inhibition of tumor progression. It is a potent inhibitor of reverse transcriptase enzyme of human immunodeficiency virus.

アプリケーション

2′,3′-Dideoxyadenosine (ddA), a specific adenylyl cyclase inhibitor, is useful in biological process and pathway studies involving adenylyl cyclase activity and cAMP pool modulation.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)