C2866

抗カンナビノイドレセプター1抗体 ウサギ宿主抗体

affinity isolated antibody, buffered aqueous solution

• MDL番号: MFCD01633082
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 化学種の反応性: human
• 利用可能性: not available in Japan
• テクニック: immunocytochemistry: suitable; immunohistochemistry (formalin-fixed, paraffin-embedded sections): 8-11 μg/mL
• UniProtアクセッション番号: P21554
• 輸送温度: dry ice
• 保管温度: −70°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... CNR1(1268) ; mouse ... Cnr1(12801) ; rat ... Cnr1(25248)

詳細

詳細

Cannabinoid receptor type 1 (CNR1) is a G protein-coupled cannabinoid receptor found in central and peripheral nervous system. CNR1 belongs to rhodopsin-like G protein-coupled receptor superfamily.

免疫原

synthetic peptide corresponding to the third cytoplasmic loop of human cannabinoid receptor 1, conjugated to KLH. The immunizing peptide has 100% homology with the rat and mouse gene.

アプリケーション

Anti-Cannabinoid Receptor 1 antibody produced in rabbit is suitable for immunocytochemistry and immunohistochemistry using formalin-fixed and paraffin-embedded sections at a concentration of 8-11μg/mL.

生物化学的／生理学的作用

CNR1 has implications in several disease states, including drug addiction, anxiety, depression, obesity, and chronic pain. Different classes of CNR1 agonists are involved in signaling pathways through the activation of specific subtypes of G proteins. It may play a key role for the treatment of negative affective state produced by alcohol withdrawal and abstinence which is critical for the maintenance of alcohol addiction. CNR1 genes also play some roles in common polymorphism (rs1049353) with potential implications in weight loss.

物理的形状

PBS溶液(pH 7.7, 0.1%アジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable