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Merck

H7909

Sigma-Aldrich

HU-210

solid (air sensitive)

別名:

(6aR-trans-3-(1, 1-ジメチルヘプチル)-6a,7,10,10a-テトラヒドロ-1-ヒドロキシ-6,6-ジメチル-6H-ジベンゾ[b,d]ピラン-9-メタノール

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About This Item

実験式(ヒル表記法):
C25H38O3
CAS番号:
分子量:
386.57
Beilstein:
4298162
MDL番号:
UNSPSCコード:
12352200
PubChem Substance ID:
NACRES:
NA.77

形状

solid (air sensitive)

品質水準

薬剤管理

USDEA Schedule I; stupéfiant (France); regulated under CDSA - not available from Sigma-Aldrich Canada

保管条件

desiccated

溶解性

DMSO: soluble

輸送温度

wet ice

保管温度

−20°C

SMILES記法

[H][C@@]12CC(CO)=CC[C@@]1([H])C(C)(C)Oc3cc(cc(O)c23)C(C)(C)CCCCCC

InChI

1S/C25H38O3/c1-6-7-8-9-12-24(2,3)18-14-21(27)23-19-13-17(16-26)10-11-20(19)25(4,5)28-22(23)15-18/h10,14-15,19-20,26-27H,6-9,11-13,16H2,1-5H3/t19-,20-/m1/s1

InChI Key

SSQJFGMEZBFMNV-WOJBJXKFSA-N

遺伝子情報

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生物化学的/生理学的作用

カンナビノイドレセプタ-アゴニスト。

特徴および利点

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, type N95 (US)


試験成績書(COA)

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以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

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O Gomez et al.
British journal of pharmacology, 163(7), 1520-1532 (2011-04-13)
The endogenous cannabinoid system participates in oligodendrocyte progenitor differentiation in vitro. To determine the effect of synthetic cannabinoids on oligodendrocyte differentiation, we exposed differentiating cultures of oligodendrocytes with cannabinoid CB(1), CB(2) and CB(1)/CB(2) receptor agonists and antagonists. The response of
S E M Lewis et al.
International journal of andrology, 35(5), 731-740 (2012-03-23)
Recent societal acceptance of cannabinoids as recreational and therapeutic drugs has posed a potential hazard to male reproductive health. Mammals have a highly sophisticated endogenous cannabinoid (ECS) system that regulates male (and female) reproduction and exo-cannabinoids may influence it adversely.
A Ottani et al.
CNS drug reviews, 7(2), 131-145 (2001-07-28)
The synthetic compound HU 210 displays a multiplicity of biochemical, pharmacological, and behavioral effects, most of which have been demonstrated to be dependent on a selective agonistic activity at CB(1) and CB(2) cannabinoid receptors and to involve the main neurotransmitter
C L Limebeer et al.
British journal of pharmacology, 167(5), 1126-1136 (2012-06-08)
Conditioned gaping reactions reflect nausea-induced behaviour in rats. Cannabinoid 1 receptor (CB(1) ) agonists interfere with the establishment of nausea-induced conditioned gaping; however, it is not known if their effects are mediated by an action at peripheral or central CB(1)
Bob Roozenbeek et al.
Critical care medicine, 40(5), 1609-1617 (2012-04-19)
The International Mission on Prognosis and Analysis of Clinical Trials and Corticoid Randomisation After Significant Head injury prognostic models predict outcome after traumatic brain injury but have not been compared in large datasets. The objective of this is study is

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