PHR1648

オメプラゾールスルホン

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: 5-メトキシ-2-{[(4-メトキシ-3,5-ジメチル-2-ピリジニル)メチル]スルホニル}-1H-ベンゾイミダゾール, オメプラゾールスルホン
• 実験式（ヒル表記法）: C₁₇H₁₉N₃O₄S
• CAS番号: 88546-55-8
• 分子量: 361.42
• Beilstein: 8347309
• MDL番号: MFCD00869772
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823531
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to Ph. Eur. O0151000; traceable to USP 1478516
• APIファミリー: omeprazole
• CofA: current certificate can be downloaded
• 包装: pkg of 30 mg
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-8°C
• SMILES記法: O=S(C1=NC2=CC(OC)=CC=C2N1)(CC3=NC=C(C)C(OC)=C3C)=O
• InChI: 1S/C17H19N3O4S/c1-10-8-18-15(11(2)16(10)24-4)9-25(21,22)17-19-13-6-5-12(23-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)
• InChI Key: IXEQEYRTSRFZEO-UHFFFAOYSA-N

詳細

詳細

品質管理目的の認定を受けた製品番号医薬品の2次標準は、薬局方の1次標準に対する便利で対費用効果の高い代替品を医薬品研究室と製薬企業に提供します。

アプリケーション

This pharmaceutical secondary standard can also be used as follows:

• Analysis of omeprazole tablets for the separation and detection of omeprazole and its related impurities by reversed-phase high-performance liquid chromatographic (RP-HPLC) method
• Determination of omeprazole and its 11 related impurities in pharmaceutical formulations by RP-HPLC method based on quality-by-design approach (QbD)
• Development of an ultra-high performance liquid chromatography-time of flight-mass spectrometry (UHPLC-TOF-MS) based method to estimate omeprazole and its related impurities in pharmaceutical formulations
• Separation and detection of omeprazole and its metabolites in human urine samples by capillary zone electrophoresis (CZE) combined with UV-Visible detector
• Estimation of related impurities of omeprazole and domperidone in their combined dosage form using the RP-HPLC method

アナリシスノート

このような2次標準は、入手可能な場合にはUSP、EP、BPの1次標準にマルチトレーサビリティを提供します。

脚注

To see an example of a Certificate of Analysis for this material enter LRAC3168 in the slot below. This is an example certificate only and may not be the lot that you receive.

おすすめ製品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

安全性情報

• ピクトグラム: GHS07,GHS09
• シグナルワード: Warning
• 危険有害性情報: H302,H411
• 注意書き: P264 - P270 - P273 - P301 + P312 - P391 - P501
• 危険有害性の分類: Acute Tox. 4 Oral - Aquatic Chronic 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable