PHR1527

デキサメサゾン 21-酢酸

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: 9α-フルオロ-16α-メチル-11β,17α,21-トリヒドロキシ-1,4-プレグナジエン-3,20-ジオン-21-酢酸, 9α-フルオロ-16α-メチルプレドニゾロン-21-酢酸, プレドニゾロン F酢酸
• 実験式（ヒル表記法）: C₂₄H₃₁FO₆
• CAS番号: 1177-87-3
• 分子量: 434.50
• Beilstein: 2342608
• EC Number: 214-646-8
• MDL番号: MFCD00027407
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823439
• NACRES: NA.24

特性

• 由来生物: synthetic
• 品質水準: 300
• グレード: certified reference material; pharmaceutical secondary standard
• 認証: BP; EP; USP; traceable to Ph. Eur. D0710000; traceable to USP 1176506
• 蒸気圧: <0.0000001 kPa ( 25 °C)
• APIファミリー: dexamethasone
• CofA: current certificate can be downloaded
• 包装: pkg of 1 g
• 保管条件: protect from light (20 mm aluminium crimp seal for unused portion)
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• 色: white
• mp: 460.4-464 °F (238—240°C)
• 溶解性: acetone: freely soluble; dichloromethane: slightly soluble; methanol: freely soluble; water: practically insoluble
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 輸送温度: ambient
• 保管温度: 2-30°C
• SMILES記法: [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O
• InChI: 1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1
• InChI Key: AKUJBENLRBOFTD-RPRRAYFGSA-N
• 遺伝子情報: human ... NR3C1(2908)

詳細

詳細

Dexamethasone acetate (Decadron-LA) belongs to the class of long-acting glucocorticoids. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Dexamethasone Acetate is a steroid used for the treatment of various diseases because of its anti-inflammatory and inmunosuppresor effects. It is a common component of ointments, creams, lotions, aerosols and microemulsions.

アプリケーション

Dexamethasone Acetate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography techniques.

Dexamethasone acetate is used as a pharmaceutical reference standard for the quantification the analyte in pharmaceutical formulations using liquid chromatography (LC) technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

アナリシスノート

このような2次標準は、入手可能な場合にはUSP、EP、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAA3645 in the slot below. This is an example certificate only and may not be the lot that you receive.

おすすめ製品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Danger
• 危険有害性情報: H360FD
• 注意書き: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危険有害性の分類: Repr. 1B
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable