PHR1224

6-アミノカプロン酸

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: ε-アミノカプロン酸, 6-アミノヘキサン酸, EACA
• 化学式: H₂N(CH₂)₅CO₂H
• CAS番号: 60-32-2
• 分子量: 131.17
• Beilstein: 906872
• EC Number: 200-469-3
• MDL番号: MFCD00008238
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823230
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to Ph. Eur. A0420000; traceable to USP 1021000
• APIファミリー: aminocaproic acid
• CofA: current certificate can be downloaded
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• mp: 207-209 °C (dec.) (lit.)
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: 2-30°C
• SMILES記法: NCCCCCC(O)=O
• InChI: 1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
• InChI Key: SLXKOJJOQWFEFD-UHFFFAOYSA-N
• 遺伝子情報: human ... PLAT(5327) , PLG(5340)

詳細

詳細

Aminocaproic acid is a synthetic inhibitor of fibrinolysis and is utilized for the control of excessive bleeding in patients with amegakaryocytic thrombocytopenia.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

アプリケーション

Aminocaproic acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by fluorimetry and in bulk and injectable forms using colorimetric method.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

リシン類縁体です。プラスミンを速やかに分解させることで、プラスミノーゲンの活性化とその後の線維素溶解を阻害します。活性化血小板へのプラスミノーゲンの結合を阻害することが報告されています。初期の報告では、補体第一成分の活性化を阻害することも示されています。カルボキシペプチダーゼBに結合して不活性化させます。

アナリシスノート

このような2次標準は、USP、EP（PhEur）、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAA9036 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable