15527

グリシン

meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)

• 別名: アミノエタン酸, アミノ酢酸, グリココール
• 化学式: NH₂CH₂COOH
• CAS番号: 56-40-6
• 分子量: 75.07
• Beilstein: 635782
• EC Number: 200-272-2
• MDL番号: MFCD00008131
• UNSPSCコード: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57647473
• NACRES: NA.21

特性

• 品質水準: 200
• アッセイ: 99-101% (based on anhydrous substance)
• 形状: crystalline powder
• 品質: meets analytical specification of Ph. Eur., BP, USP
• テクニック: IR spectroscopy: suitable
• 不純物: hydrolyzable substances, complies; organic volatile impurities, complies (GC); residual solvents, complies; ≤0.001% heavy metals (as Pb); ≤1.0% ninhydrin-positive substances
• 強熱残分: ≤0.1% (as SO₄)
• 損失: ≤0.2% loss on drying, 105 °C, 2 h
• 色: white
• pH: 5.9-6.4 (20 °C, 5%)
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• 溶解性: H₂O: soluble 25 gm in 100 ml at 25 degrees c; H₂O: soluble 39.1 gm in 100 ml at 50 degrees c; alcohol: soluble 0.06 gm in 100 gm (Absolute); pyridine: soluble 164 parts; alcohol: very slightly soluble; diethyl ether: very slightly soluble
• 微量陰イオン: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• 適合性: complies for appearance of solution; complies for reaction against H₂SO₄; in accordance for identity (IR)
• SMILES記法: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• InChI Key: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• 遺伝子情報: rat ... Grin2a(24409)

詳細

アプリケーション

Glycine was used for preparing platelets from whole-blood samples and study the stimulation of cytokine expression in leukocytes. It was used for biochemical and tolerance tests.

生物化学的／生理学的作用

Glycine has a pivotal role in lowering the plasma lipid levels in diabetic and obese patients by activating the CNS. During brain hypoxia glycine can stabilize the energetics disturbances in brain mitochondria. It also increases the in vitro development of porcine blastocysts when used along with glucose.

脊髄における抑制性神経伝達物質であり、NMDAレセプターのアロステリック調節因子です。

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)