SCT053
BioTracker SiRNO (Nitric Oxide)- Near Infrared Live Cell Dye
Live cell imaging dye for cellular nitric oxide (NO) localized to mitochondria and lysosome, used as an indicator of host defense, homeostasis and developmental functions.
別名:
Live cell imaging probe
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About This Item
UNSPSCコード:
12352207
NACRES:
NA.47
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アッセイ
≥98% (H-NMR)
≥98% (HPLC)
≥98% (LC/MS)
≥98% (elemental analysis)
テクニック
cell based assay: suitable
検出方法
fluorometric
詳細
Nitric oxide (No) is a reactive nitrogen species which is produced by nitric oxide synthase (NOS). NO is involved in many physiological processes including regulation of blood pressure, homeostasis, activation of immune system, neural communication, contraction of both smooth muscle and vascular tissue. Therefore, detection and quantification of NO is critical to understanding health and disease.
The BioTracker<TMSYMBOL></TMSYMBOL> SiRNO-Nitric oxide dye is a live cell near-infrared fluorescent imaging probe for detecting nitric oxide (NO). The probe targets NO specifically in the mitochondria and lysosome of living cells. The probe shows no cross reactivity to a variety of biomolecules and other reactive species including: ascorbic acid (AA), dehydroascorbic acid (DHA), methylglyoxal (MGO), GSH, Cys, Hcy, H2O2, ClO−, -OH, O2−, NO2−, and ONOO−. The SiRNO dye is pH insensitive in the range of 5.5 - 8.0, showing that it is suitable for physiological pH range. The SiRNO dye has been successfully used to detect NO in live cells, animal tissue and in vivo experiments.
Spectral Properties
Absorbance: 633nm
Emission: 650-750nm
The BioTracker<TMSYMBOL></TMSYMBOL> SiRNO-Nitric oxide dye is a live cell near-infrared fluorescent imaging probe for detecting nitric oxide (NO). The probe targets NO specifically in the mitochondria and lysosome of living cells. The probe shows no cross reactivity to a variety of biomolecules and other reactive species including: ascorbic acid (AA), dehydroascorbic acid (DHA), methylglyoxal (MGO), GSH, Cys, Hcy, H2O2, ClO−, -OH, O2−, NO2−, and ONOO−. The SiRNO dye is pH insensitive in the range of 5.5 - 8.0, showing that it is suitable for physiological pH range. The SiRNO dye has been successfully used to detect NO in live cells, animal tissue and in vivo experiments.
Spectral Properties
Absorbance: 633nm
Emission: 650-750nm
アプリケーション
Live cell fluorescent imaging
Live cell imaging dye for cellular nitric oxide (NO) localized to mitochondria and lysosome, used as an indicator of host defense, homeostasis and developmental functions.
Research Category
Cell Imaging
Cell Imaging
Research Sub Category
Live Cell Dye
Live Cell Dye
品質
Purity: ≥ 98% confirmed by HNMR, LC-MS and HPLC and elemental analysis
Molar Mass: 758.34 g/mol
Molar Mass: 758.34 g/mol
物理的形状
Lyophilized
保管および安定性
Store BioTracker SiRNO-Nitric Oxide Live Cell Dye at -20°C, desiccate and protect from light
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
SCT053:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Zhiqiang Mao et al.
Analytical chemistry, 89(18), 9620-9624 (2017-08-29)
Two-photon (TP) fluorescent probes are potential candidates for near-infrared (NIR) imaging which holds great promise in biological research. However, currently, most TP probes emit at wavelength <600 nm, which impedes their practical applications. In this work, we explored the TP
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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