AB5603A4

Anti-Sox2, Alexa Fluor^™ 488 Conjugate Antibody

from rabbit, ALEXA FLUOR^™ 488

• 別名: Transcription factor SOX-2
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: ALEXA FLUOR^™ 488
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 交差性: human
• 交差性（ホモロジーによる予測）: mouse (based on 100% sequence homology)
• テクニック: immunocytochemistry: suitable
• NCBIアクセッション番号: NP_003097
• UniProtアクセッション番号: P48431
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... SOX2(6657)

詳細

詳細

SOX2 is also known as SRY related HMG BOX gene 2. All SOX proteins have a single HMG box and bind linear DNA in a sequence-specific manner, resulting in the bending of DNA through large angles. Bending causes the DNA helix to open for some distance, which may affect binding and interactions of other transcription factors. SOX1, SOX2 and SOX3 show the closest homology to SRY. They share maximum homology within the HMG domain and are expressed mainly in the developing nervous system of the mouse. These genes share significant homology outside the HMG box also and are highly conserved throughout their evolution.

免疫原

Synthetic peptide from human Sox2.

アプリケーション

Research Category
ニューロサイエンス

Research Sub Category
転写因子

Detect Sox2 using this Anti-Sox2, Alexa Fluor 488 Conjugate Antibody validated for use in ICC.

品質

Evaluated by Immunocytochemistry in undifferentiated ReNcell VM neural progenitor cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Sox2 in undifferentiated ReNcell VM neural progenitor cells.

ターゲットの説明

The unconjugated antibody (AB5603) tested on western blot detects Sox2 in whole cell or nuclear extracts as a protein band at 34 kDa

物理的形状

Affinity purified

Purified rabbit polyclonal conjugated to Alexa Fluor^™ 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

保管および安定性

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

アナリシスノート

Control
Undifferentiated ReNcell VM neural progenitor cells

法的情報

ALEXA FLUOR is a trademark of Life Technologies

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids