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SOX2

SRY (sex determining region Y)-box 2

Synonyms:
ANOP3, MCOPS3
Species:
UniProtKB ID:
Gene ID:
  • Human(6657) Summary: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]
  • Mouse(20674) SRY-box containing gene 2
  • Rat(499593) SRY (sex determining region Y)-box 2
  • Zebrafish(378723) SRY-box containing gene 2
  • Horse(100146979) SRY (sex determining region Y)-box 2
  • domestic cat(100379629) SRY (sex determining region Y)-box 2
  • dog(488092) SRY (sex determining region Y)-box 2
  • chicken(396105) SRY (sex determining region Y)-box 2
  • cow(784383) SRY (sex determining region Y)-box 2
  • Goat(100861576) SRY (sex determining region Y)-box 2
  • sheep(101110563) SRY (sex determining region Y)-box 2
  • domestic guinea pig(100714747) SRY (sex determining region Y)-box 2
  • naked mole-rat(101723266) SRY (sex determining region Y)-box 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Sox2 Mouse mAb (245610), lyophilized, clone 245610, Calbiochem®,
Species Reactivity
human, mouse
Application
Monoclonal Anti-SOX2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL4716, purified immunoglobulin,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry

western blot
Anti-SOX2 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, goat, human, mouse, pig, rat
Application
western blot
Anti-SOX2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
flow cytometry
immunocytochemistry

immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-SOX-2 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP76, affinity isolated antibody,
Species Reactivity
bovine, chicken, dog, frog, human
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
Sox2 human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human
Sox2 TAT human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SOX2,
Species
human