494128

Ochratoxin A

≥97% (HPLC), powder, mycotoxin, Calbiochem

• 別名: Ochratoxin A
• 実験式（ヒル表記法）: C₂₀H₁₈ClNO₆
• CAS番号: 303-47-9
• 分子量: 403.81
• MDL番号: MFCD00078079
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• product name: Ochratoxin A, Ochratoxin A (OTA) is a mycotoxin that acts through mechanisms such as the inhibition of protein synthesis, and may also be mediated by organic anion transporters (OATs).
• 品質水準: 100
• アッセイ: ≥97% (HPLC)
• 形状: powder
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; protect from light
• 色: off-white
• 溶解性: DMSO: 50 mg/mL, nearly colorless
• 輸送温度: ambient
• 保管温度: 2-8°C
• InChI: 1S/C20H18ClNO6/c1-10-7-12-14(21)9-13(17(23)16(12)20(27)28-10)18(24)22-15(19(25)26)8-11-5-3-2-4-6-11/h2-6,9-10,15,23H,7-8H2,1H3,(H,22,24)(H,25,26)/t10-,15+/m1/s1
• InChI Key: RWQKHEORZBHNRI-BMIGLBTASA-N

詳細

詳細

Ochratoxin A (OTA) is a mycotoxin that acts through mechanisms such as the inhibition of protein synthesis, and may also be mediated by organic anion transporters (OATs).

Ochratoxin A (OTA) is a mycotoxin that acts through mechanisms such as the inhibition of protein synthesis, and may also be mediated by organic anion transporters (OATs). OTA is indicated to play a role in down-regulating the expression of protective enzymes against oxidative stress. It is known to accumulate in several tissues of the body but is primarily localized in the kidney where it impairs proximal tubular functions, and thereby causes nephrotoxicity, glucosuria, enzymuria, and a decrease in the transport of para-aminohippuric acid (PAH). It also acts as an immunosuppressant and as a potent teratogen and carcinogen.

警告

Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)

再構成

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

その他情報

Anzai, N., et al. 2010. Toxins2, 1381.
Chopra, M., et al. 2010. Cell Biol. Toxicol.26, 239.
Luhe, A., et al. 2002. Tox. Sci.73, 315.
Dirheimer, G., et al. 1991. IARC Swci Publ.115, 171.

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H300,H351
• 注意書き: P201 - P202 - P264 - P270 - P280 - P301 + P310
• 危険有害性の分類: Acute Tox. 2 Oral - Carc. 2
• 保管分類コード: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable