362339

Glyco-SNAP-2

A water-soluble nitric oxide (NO) donor that exhibits greater stability (t1/2 = 27 hours) than that of SNAP.

• 別名: Glyco-SNAP-2, N-(2-Deoxy-α,β-D-glucopyranose-2-)-N²-acetyl-S-nitroso-D,L-penicillaminamide
• 実験式（ヒル表記法）: C₁₃H₂₃N₃O₈S
• CAS番号: 188849-82-3
• 分子量: 381.40
• UNSPSCコード: 12352200
• PubChem Substance ID: 3413551
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• フォーム: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; protect from light
• 色: green
• 溶解性: aqueous buffer: >100 mg/mL; methanol: soluble; water: soluble
• 輸送温度: ambient
• 保管温度: −20°C
• SMILES記法: CC(=O)NC(C(=O)NC1C(C(C(OC1O)CO)O)O)C(C)(C)SN=O
• InChI: 1S/C13H23N3O8S/c1-5(18)14-10(13(2,3)25-16-23)11(21)15-7-9(20)8(19)6(4-17)24-12(7)22/h6-10,12,17,19-20,22H,4H2,1-3H3,(H,14,18)(H,15,21)
• InChI Key: MPJKBQQBYUJGPA-UHFFFAOYSA-N

詳細

詳細

A nitric oxide donor that exhibits greater stability than SNAP in aqueous medium, in both the presence and absence of EDTA. The half life of Glyco-SNAP-2 in aqueous medium is 27.4 h at room temperature, in the absence of EDTA, compared to 10.3 h for SNAP. The compound consists of a S-nitroso-N-acetylpencilamine moiety, which acts as a NO-donor, and a sugar fragment, which provides the desired hydrophobicity.

A water-soluble nitric oxide (NO) donor that exhibits greater stability (t_½ = 27 hours) than that of SNAP. Exhibits properties similar to those of Glyco-SNAP-1 (Cat. No. 362338).

生物化学的／生理学的作用

Cell permeable: no

Primary Target
Water-soluble nitric oxide (NO) donor

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Standard Handling (A)

再構成

Unstable in solution; reconstitute just prior to use.

その他情報

Hou, Y., et al. 1999. Methods Enzymol. 301, 242.
Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett.6, 2575.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable