317505

1,2-Dioctanoyl-sn-glycerol

Cell-permeable activator of protein kinase C (PKC).

• 別名: 1,2-Dioctanoyl-sn-glycerol, DOG, PKC Activator IV
• 実験式（ヒル表記法）: C₁₉H₃₆O₅
• CAS番号: 60514-48-9
• 分子量: 344.49
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• 形状: oil
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: clear colorless
• 溶解性: chloroform: soluble; ethyl acetate: soluble
• 輸送温度: wet ice
• 保管温度: −70°C
• InChI: 1S/C19H36O5/c1-3-5-7-9-11-13-18(21)23-16-17(15-20)24-19(22)14-12-10-8-6-4-2/h17,20H,3-16H2,1-2H3/t17-/m0/s1
• InChI Key: ZQBULZYTDGUSSK-KRWDZBQOSA-N

詳細

詳細

Cell-permeable activator of protein kinase C (PKC). Exhibits lower affinity for PKC_α than for other isozymes. Shown to mimic the effects of tumor-promoting phorbol diesters on mitogenesis and epidermal growth factor binding and action in intact cells.

Cell-permeable activator of protein kinase C; however, it has lower affinity for PKCa than for other isozymes. Shown to mimic the effects of tumor-promoting phorbol diesters on mitogenesis and epidermal growth factor binding and action in intact cells.

生物化学的／生理学的作用

Cell permeable: yes

Primary Target
Protein kinase C

Reversible: no

包装

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

再構成

Unstable in solution; reconstitute just prior to use.

アナリシスノート

Single spot by TLC

その他情報

Ferro, T.J., et al. 1993. Am. J. Physiol. 264, L7.
MacEwan, D.J., et al. 1993. Eur. J. Pharmacol. 246, 9.
Davis, R.J. 1985. J. Biol. Chem.260, 1562.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable