1.03893

ベンゼンスルホン酸

EMPROVE^® EXPERT

• 別名: Benzene sulphonic acid, Benzenesulphonic acid, Besylic acid, Phenylsulfonic acid, Phenylsulphonic acid
• 化学式: C₆H₅SO₃H
• CAS番号: 98-11-3
• 分子量: 158.18
• Beilstein: 742513
• EC Number: 202-638-7
• MDL番号: MFCD00011689
• UNSPSCコード: 12352005

特性

• 由来生物: synthetic
• 品質水準: 500
• 製品種目: EMPROVE^® EXPERT
• 形状: crystalline
• テクニック: API processing | cocrystal formation: suitable; API processing | salt formation: suitable
• 不純物: endotoxins, low
• アプリケーション: liquid formulation; parenterals; pharmaceutical
• SMILES記法: OS(=O)(=O)c1ccccc1
• InChI: 1S/C6H6O3S/c7-10(8,9)6-4-2-1-3-5-6/h1-5H,(H,7,8,9)
• InChI Key: SRSXLGNVWSONIS-UHFFFAOYSA-N

詳細

詳細

For protein-based therapeutics, such as monoclonal antibodies (mAbs) or plasma derived proteins, often highly concentrated protein formulations are required to meet intended dosing regimens. However, this usually comes with elevated viscosities and presents a challenge in the manufacturing process and final formulation. Our Viscosity Reduction Excipient Platform reduces the viscosity and helps overcome challenges associated with highly concentrated protein solutions.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation.
Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

アプリケーション

The Viscosity Reduction Platform is based on the combination of two new excipients, one amino acid component with one anionic component, that together can better reduce protein viscosity beyond levels achieved with single excipients. Also, combining the two components enables a balance of viscosity reduction and protein stabilization. Benzenesulfonic Acid Emprove^® Expert is part of this new proprietary technology platform.

包装

1038930500 / 500g / Glass bottle
1038931000 / 1kg / Glass bottle

法的情報

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS05,GHS07
• シグナルワード: Danger
• 危険有害性情報: H302,H314
• 注意書き: P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
• 保管分類コード: 8A - Combustible corrosive hazardous materials
• WGK: WGK 1