791647C

15:0-18:1-d7 DG

Avanti Research^™ - A Croda Brand 791647C

• 別名: 1-pentadecanoyl-2-oleyol(d7)-sn-glycerol
• 実験式（ヒル表記法）: C₃₆H₆₁D₇O₅
• CAS番号: 2097561-14-1
• 分子量: 587.97
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• アッセイ: >99% (TLC)
• 形状: liquid
• 包装: pkg of 1 × 1 mL (791647C-1mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand 791647C
• 濃度: 1 mg/mL (791647C-1mg)
• 輸送温度: dry ice
• 保管温度: −20°C

詳細

詳細

15:0-18:1-d7 DG (1-pentadecanoyl-2-oleyol(d7)-sn-glycerol) is a deuterated derivative of 15:0-18:1-DG, with deuteration in the oleic acid bonded to glycerol in sn-2 position. Pentadecanoic is bonded to sn-1 position. Diacylglycerols (DAG) are neutral lipids that carry fatty acid esterification. DAG is synthesized from the catabolic cleavage of headgroups of phospholipids. It is a small lipid and is membrane-associated.

This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH^™ LIPIDOMIX^™ Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

アプリケーション

15:0-18:1-d7 DG (1-pentadecanoyl-2-oleyol(d7)-sn-glycerol) has been used:

• as an internal standard to spike skeletal muscle samples for liquid chromatography-mass spectroscopy (LC-MS) analysis
• as a lipid standard in mass spectroscopy for the identification of lipids in mitochondria and lipid droplets
• in the egg yolk lipid extraction as an internal standard for mass spectroscopy analysis

生物化学的／生理学的作用

Diacylglycerols (DAG) are lipid messengers that participate in metabolic events. Altered levels, especially accumulation of DAG is implicated in insulin resistance. DAG serves as lipid modules for complex lipid synthesis. Protein kinase C (PKC) modulates DAG by interacting through its C1 domain. Impairment in DAG production is correlated to the pathology of Alzheimer′s disease, cancer and immune system diseases.

包装

2 mL Amber Glass Sealed Ampule (791647C-1mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC

SPLASH is a trademark of Avanti Polar Lipids, LLC

安全性情報

• ピクトグラム: GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• 注意書き: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• 危険有害性の分類: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• ターゲットの組織: Central nervous system, Liver,Kidney
• 保管分類コード: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• 引火点(°F): does not flash
• 引火点(℃): does not flash