QBD10505

Azido-dPEG^®₁₂-NHS ester

• 別名: Polyethylene glycol
• 実験式（ヒル表記法）: C₃₁H₅₆N₄O₁₆
• 分子量: 740.79
• MDL番号: MFCD13184947
• UNSPSCコード: 12352108
• PubChem Substance ID: 329823933
• NACRES: NA.22

特性

• アッセイ: >90%
• フォーム: solid or viscous liquid
• 反応適合性: reaction type: click chemistry; reagent type: cross-linking reagent; reaction type: click chemistry
• ポリマー構造: shape: linear; functionality: heterobifunctional
• 輸送温度: ambient
• 保管温度: −20°C
• SMILES記法: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])ON1C(CCC1=O)=O

詳細

特徴および利点

The azido-dPEG^®₁₂-NHS ester contains an azide function on one end of a single molecular weight dPEG^® spacer (47.2 Å) and NHS ester group on the other end of the spacer. The dPEG^® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. N-hydroxysuccinimide (NHS) ester readily reacts with amines in aqueous solution or organic solvent. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

法的情報

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable