L021000

DCA脱保護

with Dichloromethane

• UNSPSCコード: 41116004
• NACRES: NA.21

特性

• タイプ: for DNA synthesis; for DNA synthesis
• 製品種目: Proligo Reagents
• 形状: liquid
• 保管条件: dry at room temperature
• 濃度: 42.2-51.6 g/L (DCA content, titration)
• 不純物: ≤200 ppm water content (Karl Fischer)
• 色: clear

詳細

詳細

Deblock solution contains dichloroacetic acid (DCA) in dichloromethane that assists in the removal of the dimethoxytrityl (DMT) protecting group from the 5′hydroxyl moiety of nucleotides already incorporated into the growing nucleic acid, before the addition of the next phosphoramidite. Removal of the DMT allows the unprotected 5′hydroxyl moiety to react with a new phosphoramidite in a subsequent extension reaction.

調製ノート

ジクロロメタン/ジクロロ酢酸 97/3 (v/v)

その他情報

Deblock solution containing dichloroacetic acid (DCA) in dichloromethane removes the dimethoxytrityl (DMT) protecting group from the 5′hydroxyl moiety of nucleotides already incorporated into the growing nucleic acid, prior to the addition of the next phosphoramidite. Removal of the DMT allows the unprotected 5′hydroxyl moiety to react with a new phosphoramidite in a subsequent extension reaction.

安全性情報

• ピクトグラム: GHS08,GHS05,GHS07
• シグナルワード: Danger
• 危険有害性情報: H315,H318,H336,H351,H360FD,H362
• 注意書き: P202 - P263 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• 危険有害性の分類: Carc. 2 - Eye Dam. 1 - Lact. - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Central nervous system
• 保管分類コード: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable