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アッセイ
98%
フォーム
solid
mp
202-205 °C (lit.)
SMILES記法
Nc1n[nH]c(N)n1
InChI
1S/C2H5N5/c3-1-5-2(4)7-6-1/h(H5,3,4,5,6,7)
InChI Key
PKWIYNIDEDLDCJ-UHFFFAOYSA-N
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詳細
3,5-Diamino-1,2,4-triazole, also known as Guanazole is a heterocyclic compound and is commonly used as a building block in the synthesis of gallium complexes of tert-butyl-substituted acyclic and cyclic compounds. It is also being investigated as a corrosion inhibitor for copper.
アプリケーション
DNA合成阻害剤。
シグナルワード
Warning
危険有害性情報
危険有害性の分類
Aquatic Chronic 2 - Repr. 2 - STOT RE 2
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
D26202-VAR:
D26202-100G:
D26202-BULK:
D26202-10G:
D26202-5KG:
D26202-25G:
D26202-1KG:
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V M Kolb et al.
Journal of molecular evolution, 38, 549-557 (1994-01-01)
Urazole is a five-membered heterocyclic compound which is isosteric with uracil's hydrogen-bonding segment. Urazole reacts spontaneoulsy with ribose (and other aldoses) to give a mixture of four ribosides: alpha and beta pyranosides and furanosides. This reaction occurs in aqueous solution
A A Alhaider et al.
Journal of pharmaceutical sciences, 71(1), 89-94 (1982-01-01)
A series of guanazole prodrugs, which are less water soluble than the parent compound and have relatively higher molecular weights, was recently synthesized, and their antineoplastic activities were measured in vitro. In present work, the ionization constants and partition coefficients
C Loganathan et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 173, 837-842 (2016-11-07)
Detection of a chromogenic insecticide, malachite green (MG) using 3,5-diamino-1,2,4-triazole capped gold nanoparticles (DAT-AuNPs) by both naked eye and spectrophotometry was described in this paper. The DAT-AuNPs were prepared by wet chemical method and show absorption maximum at 518nm. The
Inhibition of ribonucleotide reductases encoded by herpes simplex viruses.
T Spector
Pharmacology & therapeutics, 31(3), 295-302 (1985-01-01)
G Tipples et al.
Journal of bacteriology, 173(16), 4932-4940 (1991-08-01)
Chlamydiae are obligate intracellular bacteria that are dependent on eukaryotic host cells for ribonucleoside triphosphates but not deoxyribonucleotide triphosphates. Ribonucleotide reductase is the only enzyme known to catalyze the direct conversion of a ribonucleotide to a deoxyribonucleotide. Hydroxyurea inhibits ribonucleotide
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