804568

(R,S)-Bode Kinetic Resolution Catalyst

• 別名: (4aR,9aS)-6-Bromo-4-hydroxy-4,4a,9,9a-tetrahydroindeno[2,1-b][1,4]oxazin-3(2H)-one
• 実験式（ヒル表記法）: C₁₁H₁₀BrNO₃
• CAS番号: 1394957-71-1
• 分子量: 284.11
• MDL番号: MFCD29037020
• UNSPSCコード: 12352101
• PubChem Substance ID: 329768882
• NACRES: NA.22

特性

• フォーム: solution
• 品質水準: 100
• 官能基: bromo; ether
• 保管温度: 15-25°C
• SMILES記法: O=C(CO1)N(O)[C@@]2([H])[C@]1([H])CC3=CC=C(Br)C=C32
• InChI: 1S/C11H10BrNO3/c12-7-2-1-6-3-9-11(8(6)4-7)13(15)10(14)5-16-9/h1-2,4,9,11,15H,3,5H2/t9-,11+/m0/s1
• InChI Key: FQXSUQCCAHKURK-GXSJLCMTSA-N

詳細

アプリケーション

The following hydroxamic acid catalyst was shown by Bode and coworkers to assist in the kinetic resolution of cyclic amines through acylation of one enantiomer, which can be controlled using either the (R or S)- or (S or R)-Bode Kinetic Resolution Catalyst, both of which are also available through Sigma-Aldrich.
It can also be employed in the preparation of nonracemic piperidines by kinetic resolution using an α-hydroxy-α′, β-unsaturated ketone in the presence of a pyrrolotriazolium salt.

その他情報

Expanded substrate scope and catalyst optimization for the catalytic kinetic resolution of N-heterocycles

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302
• 注意書き: P301 + P312 + P330
• 危険有害性の分類: Acute Tox. 4 Oral
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable