699918

(R)-N-[(1R,2R)-2-(3-(3,5-ビス(トリフルオロメチル)フェニル)ウレイド)シクロヘキシル]-tert-ブチル-スルフィンアミド

96%

• 別名: [S(R)]-N-[(1R,2R)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]carbonyl]amino]cyclohexyl]-2-methyl-2-propanesulfinamide
• 実験式（ヒル表記法）: C₁₉H₂₅F₆N₃O₂S
• CAS番号: 934762-68-2
• 分子量: 473.48
• MDL番号: MFCD11656068
• UNSPSCコード: 12352002
• PubChem Substance ID: 329762164
• NACRES: NA.22

特性

• 品質水準: 100
• アッセイ: 96%
• フォーム: solid
• mp: 173-181 °C
• 官能基: amine; fluoro
• SMILES記法: CC(C)(C)S(=O)N[C@@H]1CCCC[C@H]1NC(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F
• InChI: 1S/C19H25F6N3O2S/c1-17(2,3)31(30)28-15-7-5-4-6-14(15)27-16(29)26-13-9-11(18(20,21)22)8-12(10-13)19(23,24)25/h8-10,14-15,28H,4-7H2,1-3H3,(H2,26,27,29)/t14-,15-,31-/m1/s1
• InChI Key: WMIJNZVQFOPOBW-ZHANGXNJSA-N

詳細

アプリケーション

(R)-N-[(1R,2R)-2-(3-(3,5-Bis(trifluoromethyl)phenyl)ureido)cyclohexyl]-tert-butyl-sulfinamide is a sulfinamide-urea based chiral catalyst that can be used to synthesize:

• Enantioselective homoallylic amines by asymmetric allylation of acylhydrazones with allylindium reagents.
• Tetrahydroquinolines via an asymmetric Povarov reaction.
• 2-aryl-substituted cycloalkanones by enantioselective protonation of corresponding trimethylsilyl enol ethers.

安全性情報

• 危険有害性情報: H413
• 危険有害性の分類: Aquatic Chronic 4
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)