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安全性情報

739979

Sigma-Aldrich

Resomer® RG 858 S, ポリ(D,L-ラクチド-co-グリコリド)

ester terminated, lactide:glycolide 85:15, Mw 190,000-240,000

別名:

PLGA

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About This Item

化学式:
[C3H4O2]x[C2H2O2]y
CAS番号:
26780-50-7
UNSPSCコード:
12162002
NACRES:
NA.23

品質水準

100

形状

amorphous

原料比

lactide:glycolide 85:15

分子量

Mw 190,000-240,000

劣化の時間枠

<9 months

粘度

1.3-1.7 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

保管温度

2-8°C

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChI Key

LCSKNASZPVZHEG-UHFFFAOYSA-N

詳細

RESOMER®ポリマーは、さまざまな割合のラクチドモノマーとグリコリドモノマー、PLA立体化学、および末端基官能化で構成される生体吸収型脂肪族ポリエステルです。このラクチドとグリコリドの生分解性ホモポリマーとコポリマーは、分解時間の長い非常に硬質で固い半結晶材料から分解時間が短い柔軟な非晶質材料まで、さまざまな特性を発揮します。

アプリケーション

バガス由来セルロース混合Electrospun Resomer® X 206 Sは、組織工学におけるスキャフォールド（足場）として使用できます。
制御された放出

特徴および利点

生物活性剤の制御された放出、縫合や生体吸収性の移植可能なデバイス。

法的情報

Evonik社の製品です。
RESOMER is a registered trademark of Evonik Rohm GmbH

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保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

739979-VAR:
739979-1G:
739979-BULK:
739979-5G:

最新バージョンのいずれかを選択してください：

試験成績書（COA）

Lot/Batch Number
BCCG7417
BCCF7604
BCCC6904
BCBV9308
BCCB3648

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以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

RESOMER??Biodegradeable Polymers for Sutures, Medical Devices, Drug Delivery Systems and Tissue Engineering
Mader K
Material Matters, 6(3), 62-62 (2011)
Rongcai Liang et al.
International journal of pharmaceutics, 454(1), 344-353 (2013-07-23)
Peptide or protein degradation often occurs when water flows into the dosage form. The aim of this study was to investigate the effect of water on exenatide acylation in poly(lactide-co-glycolide) (PLGA) microspheres. Exenatide-loaded PLGA microspheres were incubated at different relative
Shu-Chun Chuang et al.
Parasites & vectors, 6, 34-34 (2013-02-13)
Current development efforts of subunit vaccines against Toxoplasma gondii, the etiological agent of toxoplasmosis, have been focused mainly on tachyzoite surface antigen 1 (SAG1). Since microparticles made from poly (lactide-co-glycolide) (PLG) polymers have been developed as safe, potent adjuvants or
Vanna Sanna et al.
International journal of nanomedicine, 7, 5501-5516 (2012-10-25)
Resveratrol, like other natural polyphenols, is an extremely photosensitive compound with low chemical stability, which limits the therapeutic application of its beneficial effects. The development of innovative formulation strategies, able to overcome physicochemical and pharmacokinetic limitations of this compound, may
Mani Gajendiran et al.
Colloids and surfaces. B, Biointerfaces, 104, 107-115 (2013-01-10)
A series of biodegradable low molecular weight PLGA-PEG-PLGA tri-block copolymers have been synthesized in powder form. The anti-tuberculosis drug Isoniazid (INH) loaded polymeric core-shell nanoparticles (CSNPs) have been prepared by sonication followed by water-in-oil-in-water (w/o/w) double emulsification technique. The nanoparticles
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資料

Poly(Glycerol Sebacate) in Tissue Engineering and Regenerative Medicine

The world of commercial biomaterials has stagnated over the past 30 years as few materials have successfully transitioned from the bench to clinical use. Synthetic aliphatic polyesters have continued to dominate the field of resorbable biomaterials due to their long history and track record of approval with the U.S. Food and Drug Administration (FDA).

Biodegradable Polyester-based Nanoparticle Formation by Miniemulsion Technique

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

Biodegradable Polyester-based Nanoparticle Formation by Miniemulsion Technique

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

Biodegradable Polyester Based Nanoparticle Formation by Miniemulsion Technique

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

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