677191

(R)-(+)-α,α-ジフェニル-2-ピロリジンメタノールトリメチルシリルエーテル

96%

• 別名: (2R)-2-[Diphenyl[(trimethylsilyl)oxy]methyl]pyrrolidine, (R)-α,α-Diphenylprolinol trimethylsilyl ether, (R)-2-[Diphenyl(trimethylsilanyloxy)methyl]pyrrolidine
• 実験式（ヒル表記法）: C₂₀H₂₇NOSi
• CAS番号: 943757-71-9
• 分子量: 325.52
• MDL番号: MFCD09265100
• UNSPSCコード: 12352005
• PubChem Substance ID: 24885355
• NACRES: NA.22

特性

• アッセイ: 96%
• フォーム: solid
• 光学活性: [α]22/D +52±5°, c = 1 in chloroform
• 屈折率: n20/D 1.5509
• 密度: 1.0459 g/mL at 25 °C
• 官能基: phenyl
• 保管温度: 2-8°C
• SMILES記法: C[Si](C)(C)OC([C@H]1CCCN1)(c2ccccc2)c3ccccc3
• InChI: 1S/C20H27NOSi/c1-23(2,3)22-20(19-15-10-16-21-19,17-11-6-4-7-12-17)18-13-8-5-9-14-18/h4-9,11-14,19,21H,10,15-16H2,1-3H3/t19-/m1/s1
• InChI Key: RSUHWMSTWSSNOW-LJQANCHMSA-N

詳細

詳細

(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether is a diarylprolinol silyl ether organocatalyst.

アプリケーション

(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether can be used as a catalyst to synthesize:

• Glycofused tricyclic derivatives, which are used in the development of amyloid β-peptide diagnostic tools.
• Cyclohexene carbaldehyde derivatives by reacting benzoylnitromethane with aliphatic enals.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves