545872

(R)-(+)-Aminoglutethimide

97%

• 実験式（ヒル表記法）: C₁₃H₁₆N₂O₂
• CAS番号: 55511-44-9
• 分子量: 232.28
• UNSPSCコード: 12352005
• PubChem Substance ID: 24878857
• NACRES: NA.22

特性

• 品質水準: 100
• アッセイ: 97%
• 光学活性: [α]20/D +160°, c = 1 in methanol
• mp: 115.5-119.5 °C (lit.)
• SMILES記法: CC[C@@]1(CCC(=O)NC1=O)c2ccc(N)cc2
• InChI: 1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)/t13-/m1/s1
• InChI Key: ROBVIMPUHSLWNV-CYBMUJFWSA-N
• 遺伝子情報: human ... CYP17A1(1586) , CYP19A1(1588)

詳細

アプリケーション

(R)-(+)-Aminoglutethimide can be used:

• As a building block for the development of cephalosporin based prodrug for antibody-directed enzyme prodrug therapy (ADEPT).
• To prepare (R)-3-ethyl-3-(4-(3,4,5-trimethoxybenzylamino)phenyl)piperidine-2,6-dione by reacting with 3,4,5-trimethoxybenzylamine via deaminative coupling reaction.
• To synthesize (R)-2-fluoro-2-(4-methoxyphenyl)-N-(R)-(+)-aminoglutethimide by enantioselective α-fluorination.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves