437786

ジエチルクロロマロナート

95%

• 化学式: ClCH(CO₂C₂H₅)₂
• CAS番号: 14064-10-9
• 分子量: 194.61
• EC Number: 237-913-0
• MDL番号: MFCD00009140
• UNSPSCコード: 12352100
• PubChem Substance ID: 24867397
• NACRES: NA.22

特性

• 品質水準: 100
• アッセイ: 95%
• 形状: liquid
• 屈折率: n20/D 1.432 (lit.)
• 密度: 1.204 g/mL at 25 °C (lit.)
• 官能基: chloro; ester
• SMILES記法: CCOC(=O)C(Cl)C(=O)OCC
• InChI: 1S/C7H11ClO4/c1-3-11-6(9)5(8)7(10)12-4-2/h5H,3-4H2,1-2H3
• InChI Key: WLWCQKMQYZFTDR-UHFFFAOYSA-N

詳細

詳細

Diethyl chloromalonate (Diethyl α-chloromalonate) is a 2-halo-1,3-dicarbonyl compound. It participates in K₂CO₃-catalyzed domino reactions (Michael alkylation, Mannich alkylation, and aldol alkylation) of salicylic aldehyde derivatives to afford functionalized 2,3-dihydrobenzofurans. It reacts with Cs₂CO₃ in the presence of elemental S₈ or Se_n to afford the corresponding diethyl thioxo- or selenoxomalonates, which can be trapped in situ with various 1,3-dienes.

安全性情報

• ピクトグラム: GHS05,GHS07,GHS09
• シグナルワード: Danger
• 危険有害性情報: H314,H335,H400
• 注意書き: P261 - P271 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• 危険有害性の分類: Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• 引火点(°F): 235.4 °F - closed cup
• 引火点(℃): 113 °C - closed cup
• 個人用保護具 (PPE): Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter