318434

3,3′-Dipropylthiacarbocyanine iodide

98%

• 別名: 3-Propyl-2-[3-[3-propyl-2(3H)benzothiazolylidene]-1-propenyl]benzothiazolium iodide, DiSC₃(3)
• 実験式（ヒル表記法）: C₂₃H₂₅IN₂S₂
• CAS番号: 53336-12-2
• 分子量: 520.49
• Beilstein: 3842440
• MDL番号: MFCD00013340
• UNSPSCコード: 12171500
• PubChem Substance ID: 329753928
• NACRES: NA.47

特性

• アッセイ: 98%
• 形状: crystalline powder
• mp: 288 °C (dec.) (lit.)
• 溶解性: chloroform/methanol: 10 mg/mL, clear
• λmax: 559 nm
• &ε; （減衰係数）: 163120 at 599 nm in methanol at 0.00463 g/L; 17425 at 298 nm in methanol at 0.00463 g/L; 40246 at 220 nm in methanol at 0.00463 g/L
• 蛍光検出: λ_ex 559 nm; λ_em 575 nm in methanol
• アプリケーション: diagnostic assay manufacturing; hematology; histology
• 保管温度: room temp
• SMILES記法: [I-].CCCN1C(\Sc2ccccc12)=C\C=C\c3sc4ccccc4[n+]3CCC
• InChI: 1S/C23H25N2S2.HI/c1-3-16-24-18-10-5-7-12-20(18)26-22(24)14-9-15-23-25(17-4-2)19-11-6-8-13-21(19)27-23;/h5-15H,3-4,16-17H2,1-2H3;1H/q+1;/p-1
• InChI Key: JGTCEHAVVINOPG-UHFFFAOYSA-M

詳細

詳細

3,3′-Dipropylthiacarbocyanine iodide is a carbocyanine fluorescent dye sensitive to membrane potential. This cyanine dye plays a vital role as an optical probe of membrane potential. An increase in the fluorescence intensity of the dye indicates depolarization of the plasma membrane potential.

アプリケーション

3,3′-Dipropylthiacarbocyanine iodide has been used to determine bacterial membrane permeability by the effect of electrochemical scaffold treatment.

生物化学的／生理学的作用

The embrane potential sensitive dye, 3,3′dipropylthiacarbocyanine iodide enters only depolarized cells, where it binds reversibly to lipid-rich intracellular components.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves