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Merck

AR

androgen receptor

別名:
AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
Species:
UniProtKB ID:
遺伝子ID:
  • Human(367) Summary: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(11835) androgen receptor
  • Rat(24208) androgen receptor
  • Zebrafish(100005148) androgen receptor
  • chicken(422165) androgen receptor
  • fruit fly(44503) abdomen rotatum
  • domestic cat(101081787) androgen receptor
  • cow(280675) androgen receptor
  • Horse(100033980) androgen receptor
  • domestic cat(751827) androgen receptor
  • dog(403588) androgen receptor
  • Goat(100860827) androgen receptor
  • Domestic Rabbit(100009193) androgen receptor
  • sheep(443042) androgen receptor
  • domestic guinea pig(100726891) androgen receptor

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Small Molecule - Activator

Product Number
詳細
Species
α-エストラジオール, powder, ≥98% (TLC),
Species
human, rat
19-ノルエチンドロン, ≥98%, powder,
Species
human, rat
プロピレングリコールモノメチルエーテルアセタート, ReagentPlus®, ≥99.5%,
Species
human
レスベラトロール, ≥99% (HPLC),
Species
human, rat, mouse
ジエチルスチルベストロール, ≥99% (HPLC),
Species
human, mouse, rat

Small Molecule - Agonist

Product Number
詳細
Species
テストステロン 溶液, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
オキサンドロロン, ≥98% (HPLC),
Species
human
Methandienone solution, 1.0 mg/mL in 1,2-dimethoxyethane, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
エナント酸テストステロン, United States Pharmacopeia (USP) Reference Standard,
Species
human
Testosterone cypionate, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
詳細
Species
バニリン, ReagentPlus®, 99%,
Species
rat
ベンゾフェノン, ReagentPlus®, 99%,
Species
rat
Methyl Paraben, PESTANAL®, analytical standard,
Species
rat
4-ヒドロキシ安息香酸プロピル, ≥99%,
Species
rat
バニリン, natural, ≥97%, FCC, FG,
Species
rat

Antibodies

Product Number
詳細
交差性
アプリケーション
Anti-phospho-Androgen Receptor (Ser81) Antibody, rabbit monoclonal, culture supernatant, Upstate®,
交差性
human
アプリケーション
western blot
Anti-Androgen Receptor antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
抗アンドロゲンレセプター抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human
アプリケーション
ChIP
ELISA

immunohistochemistry

western blot
抗AR抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Monoclonal Anti-AR antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL9255, purified immunoglobulin, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot

Small Molecule - Blocker

Product Number
詳細
Species
フルタミド, ,
Species
mouse, rat, human

Small Molecule - Inhibitor

Product Number
詳細
Species
trans-カルコン, 97%,
Species
rat, human
4-(ベンジルオキシ)フェノール, 98%,
Species
rat, human
Galeterone, ≥98% (HPLC),
Species
human
スピロノラクトン, 97.0-103.0%,
Species
rat, human
プロピオン酸テストステロン, solid,
Species
human, rat

Small Molecule - Ligand

Product Number
詳細
Species
テストステロン, purum, ≥99.0% (HPLC),
Species
human
テストステロン, VETRANAL®, analytical standard,
Species
human
4-ヒドロキシエストラジオール, ,
Species
rat, human
タモキシフェン, ≥99%,
Species
human, rat
テストステロン, ≥98%,
Species
mouse, human, rat

Proteins

Product Number
詳細
Species
アンドロゲンレセプター(650-920), ヒト, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Species
human
Androgen Receptor, His•Tag®, Human, Recombinant, S. frugiperda, recombinant human, expressed in S. frugiperda,
Species
human

esiRNA

Product Number
詳細
Species
MISSION® esiRNA, targeting human AR,
Species
human
MISSION® esiRNA, targeting mouse Ar,
Species
mouse