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Merck

W290904

Sigma-Aldrich

胡椒碱

≥95%, FG

别名:

1-胡椒酰哌啶

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About This Item

经验公式(希尔记法):
C17H19NO3
CAS号:
分子量:
285.34
FEMA號碼:
2909
Beilstein:
90741
EC號碼:
歐洲委員會號碼:
492
MDL號碼:
分類程式碼代碼:
12164502
PubChem物質ID:
Flavis號碼:
14.003
NACRES:
NA.21
感官的:
fatty; pepper
等級:
FG
Halal
Kosher
生物源:
Piper nigrum L.
食物過敏原:
no known allergens

生物源

Piper nigrum L.

品質等級

等級

FG
Halal
Kosher

法律遵循

EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 172.515

化驗

≥95%

形狀

powder, crystals or granules

mp

131-135 °C (lit.)

應用

flavors and fragrances

文件

see Safety & Documentation for available documents

食物過敏原

no known allergens

感官的

fatty; pepper

SMILES 字串

O=C(\C=C\C=C\c1ccc2OCOc2c1)N3CCCCC3

InChI

1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2+,7-3+

InChI 密鑰

MXXWOMGUGJBKIW-YPCIICBESA-N

基因資訊

human ... CYP3A4(1576)

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生化/生理作用

Piperine, a major component of black pepper extracts, shown to have potential for inhibiting fat cell formation.

象形圖

Exclamation markEnvironment

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Aquatic Chronic 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析证书(COA)

Lot/Batch Number

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Ui-Hyun Park et al.
Journal of agricultural and food chemistry, 60(15), 3853-3860 (2012-04-03)
This study investigated the antiadipogenic activity of black pepper extract and its constituent piperine in 3T3-L1 preadipocytes as well as the underlying molecular mechanisms. Both black pepper extract and piperine, without affecting cytotoxicity, strongly inhibited the adipocyte differentiation of 3T3-L1
Janine Zaugg et al.
Journal of natural products, 73(2), 185-191 (2010-01-21)
A plant extract library was screened for GABA(A) receptor activity making use of a two-microelectrode voltage clamp assay on Xenopus laevis oocytes. An ethyl acetate extract of black pepper fruits [Piper nigrum L. (Piperaceae) 100 microg/mL] potentiated GABA-induced chloride currents
Hyung Gyun Kim et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(7), 2342-2348 (2012-05-01)
Piperine is a major component of black (Piper nigrum Linn) and long (Piper longum Linn) peppers, and is widely used as a traditional food and medicine. It also exhibits a variety of biological activities, which include antioxidant, anti-tumor and anti-pyretic
Clara Grosso et al.
Phytochemical analysis : PCA, 24(2), 141-147 (2012-09-19)
Depression is a mental disease causing large personal and socio-economic problems, and new improved drugs are therefore needed. Selective monoamine oxidase A (MAO-A) inhibitors are potential anti-depressants, but discovering new MAO-A inhibitors from natural sources by bioassay-guided approaches are a
Sophia Khom et al.
Biochemical pharmacology, 85(12), 1827-1836 (2013-04-30)
The action of piperine (the pungent component of pepper) and its derivative SCT-66 ((2E,4E)-5-(1,3-benzodioxol-5-yl))-N,N-diisobutyl-2,4-pentadienamide) on different gamma-aminobutyric acid (GABA) type A (GABA(A)) receptors, transient-receptor-potential-vanilloid-1 (TRPV1) receptors and behavioural effects were investigated. GABA(A) receptor subtypes and TRPV1 receptors were expressed in

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