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品質等級
化驗
≥97%
形狀
crystalline
powder, crystals or chunks
solid
mp
131-135 °C (lit.)
SMILES 字串
O=C(\C=C\C=C\c1ccc2OCOc2c1)N3CCCCC3
InChI
1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2+,7-3+
InChI 密鑰
MXXWOMGUGJBKIW-YPCIICBESA-N
基因資訊
human ... CYP3A4(1576)
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應用
Reactant for synthesis of:
- Dimeric amide alkaloids
- Piperoyl-amino acid conjugates used for antileishmanial activity
- Piperine derived amides with TRPV1 activity
- Piperine analogues as S. aureus NorA efflux pump inhibitors
- Bioactive conjugates of curcumin with antimicrobial and antiproliferative properties
- Piperine derivatives for use as trypanocidal agents
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral - Aquatic Chronic 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
V. R. S. Rao, et al.,
Tetrahedron, 67, 1885-1892 (2011)
Jiu-Wang Yu et al.
Molecular diversity, 25(1), 233-248 (2020-03-05)
Piperine is the main active component of Piper longum L., which is also the main component of anti-sciatica Mongolian medicine Naru Sanwei pill. It has many pharmacological activities such as anti-inflammatory and immune regulation. This paper aims to preliminarily explore
Janine Zaugg et al.
Journal of natural products, 73(2), 185-191 (2010-01-21)
A plant extract library was screened for GABA(A) receptor activity making use of a two-microelectrode voltage clamp assay on Xenopus laevis oocytes. An ethyl acetate extract of black pepper fruits [Piper nigrum L. (Piperaceae) 100 microg/mL] potentiated GABA-induced chloride currents
Welisson da Silva Ferreira et al.
Bioorganic & medicinal chemistry, 16(6), 2984-2991 (2008-01-30)
We herein describe the synthesis and characterization of nine new 1,3,4-thiadiazolium-2-phenylamine chlorides derived from natural piperine. We evaluate their toxic effects against the different evolutive forms of Trypanosoma cruzi, and the host cell (murine macrophages). The results obtained show that
Clara Grosso et al.
Phytochemical analysis : PCA, 24(2), 141-147 (2012-09-19)
Depression is a mental disease causing large personal and socio-economic problems, and new improved drugs are therefore needed. Selective monoamine oxidase A (MAO-A) inhibitors are potential anti-depressants, but discovering new MAO-A inhibitors from natural sources by bioassay-guided approaches are a
Global Trade Item Number
| 货号 | GTIN |
|---|---|
| P49007-1G | 4061834375333 |
| P49007-25G | |
| P49007-5G | 4061834375364 |
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