Skip to Content
Merck
All Photos(2)

Key Documents

More Documents

914339

Sigma-Aldrich

Fmoc-L-Lys(Nvoc)-OH

≥98%

Synonym(s):

(S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)-6-((4,5-dimethoxy-2-nitrobenzyloxy)carbonylamino)hexanoic acid, N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-(((4,5-dimethoxy-2-nitrobenzyl)oxy)carbonyl)-L-lysine, Lysine with photoremovable NVOC, Photocaged amino acid, Photocleavable lysine derivative

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C31H33N3O10
CAS Number:
150571-28-1
Molecular Weight:
607.61
MDL number:
MFCD08064317
UNSPSC Code:
12352209

Quality Level

100

Assay

≥98%

form

powder

mp

108 °C (decomp.)

storage temp.

2-8°C

Application

Fmoc-L-Lys(Nvoc)-OH is a lysine derivative compatible with solid-phase peptide synthesis (SPPS). The photolabile, N-terminal protecting group nitroveratryloxycarbonyl (NVOC) can be cleaved by photolysis at 350 nm. Photocaged amino acids such as these are useful in the synthesis of photocleavable chemical tools for spatial and temporal control over released molecules in biological applications.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Other Notes

Total chemical synthesis of photoactivatable proteins for light-controlled manipulation of antigen-antibody interactions

In situ cell manipulation through enzymatic hydrogel photopatterning

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Shan Tang et al.
Chemical science, 7(3), 1891-1895 (2016-03-01)
We report the chemical synthesis of the first photo-activatable protein antigen that can be used to study antigen-antibody interaction mediated responses in B cells. This strategy facilitated fine tuning of the caged protein antigen to optimize its bioactivity and photochemical
Katarzyna A Mosiewicz et al.
Nature materials, 12(11), 1072-1078 (2013-10-15)
The physicochemical properties of hydrogels can be manipulated in both space and time through the controlled application of a light beam. However, methods for hydrogel photopatterning either fail to maintain the bioactivity of fragile proteins and are thus limited to

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service