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Key Documents

RES0197M-A7

SAFC

MOPS

Produzione farmaceutica

Sinonimo/i:

Acido 3-(N-morfolino) propansolfonico, Acido 4-morfolinpropansolfonico

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About This Item

Formula empirica (notazione di Hill):
C7H14NNaO4S
Numero CAS:
Peso molecolare:
231.25
Numero MDL:
Codice UNSPSC:
12161700
NACRES:
NA.21

Origine biologica

synthetic

Livello qualitativo

Forma fisica

powder

tecniche

cell culture | mammalian: suitable

Impurezze

Endotoxin and microbial, tested

Intervallo di pH utile

6.5-7.9

pKa (25 °C)

7.2

Compatibilità

suitable for manufacturing use

Attività estranea

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

Stringa SMILE

[Na+].[O-]S(=O)(=O)CCCN1CCOCC1

InChI

1S/C7H15NO4S.Na/c9-13(10,11)7-1-2-8-3-5-12-6-4-8;/h1-7H2,(H,9,10,11);/q;+1/p-1
MWEMXEWFLIDTSJ-UHFFFAOYSA-M

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Descrizione generale

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Applicazioni

MOPS Sodium is a biological buffer also referred to as a “Propane Sultone” buffer. The pKa of MOPS Sodium is 7.01 which make it an ideal candidate for medias and protein based buffer formulations to maintain a stable environment in solution. MOPS Sodium is considered to be non-toxic to culture cell lines and provides high solution clarity.

MOPS Sodium is used in cell culture media, biopharmaceutical buffer formulations both upstream and downstream and diagnostic reagents. MOPS based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components. MOPSO based buffers have been described for fixation of cells from urine samples.

Confezionamento

Product is available in the following package sizes:
RES0197M-A701X: 100g container
RES0197M-A702X 1kg container
RES0197M-A704X: 10kg container
RES0197M-A705X: 25kg container

Note legali

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Sostituito da

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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MOPS anhydrous, free-flowing, Redi-Dri™, ≥99.5%

Sigma-Aldrich

RDD003

MOPS

MOPS ≥99.5% (titration)

Sigma-Aldrich

M1254

MOPS

HEPES

SAFC

RES6003H-B7

HEPES

HEPES

SAFC

RES6007H-A7

HEPES

MOPSO ≥99% (titration)

Sigma-Aldrich

M8389

MOPSO

Ying Hou et al.
Biotechnology progress, 31(4), 974-982 (2015-05-29)
Protein A chromatography is widely employed for the capture and purification of monoclonal antibodies (mAbs). Because of the high cost of protein A resins, there is a significant economic driving force to seek new downstream processing strategies. Membrane chromatography has

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