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O5500

Sigma-Aldrich

Osmium tetroxide

Sealed ampule.

Sinonimo/i:

Osmium(VIII)-oxide, ‘Osmic acid’

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About This Item

Formula condensata:
OsO4
Numero CAS:
20816-12-0
Peso molecolare:
254.23
Numero CE:
244-058-7
Numero MDL:
MFCD00011150
Codice UNSPSC:
12171500
ID PubChem:
57654490
NACRES:
NA.47

Densità del vapore

8.8 (vs air)

Livello qualitativo

200

Tensione di vapore

7 mmHg ( 20 °C)

Forma fisica

powder

Impiego in reazioni chimiche

reagent type: oxidant

P. eboll.

130 °C (lit.)

Punto di fusione

39.5-41 °C (lit.)

Stringa SMILE

O=[Os](=O)(=O)=O

InChI

1S/4O.Os
VUVGYHUDAICLFK-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

Osmium tetroxide (OsO4) is a heavy tetrahedral, symmetrical molecule composed of osmium, a third-row transition metal. Osmium tetroxide is both a dye, and a non-coagulant fixative agent in electron microscopy primarily used for the examination of biological tissue components in the histopathology laboratory. Specimens are postfixed with osmium testroxide to ensure preservation of the lipids.

Applicazioni

Osmium tetroxide has been used as a fixative reagent for Brevibacterium mcbrellneri, and curcumin treated human lung cancer cell lines′ observation with a scanning electron microscope. It is also suitable as a fixative for ultrastructural analysis of Toxoplasma gondii′s skeletal muscle cells.

Azioni biochim/fisiol

Osmium tetroxide chemically combines with lipids making them insoluble; only 7% of the lipids can be extracted after the fixation. Therefore, the cell membranes comprising phospholipids become black and electron-dense after fixation in osmium tetroxide. It is also used to fix small amount of fat maintained in sections during paraffin processing.

Altre note

Due to the hazardous nature of osmium tetroxide, it is recommended to use an ampule opener when using this chemical.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Skull and crossbonesCorrosion
GHS06,GHS05

Avvertenze

Danger

Indicazioni di pericolo

H300 + H310 + H330,H314

Classi di pericolo

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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