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Key Documents

75632

Sigma-Aldrich

Osmium tetroxide solution

suitable for electron microscopy, 4% in H2O

Sinonimo/i:

Osmium(IV) oxide

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About This Item

Formula condensata:
OsO4
Numero CAS:
Peso molecolare:
254.23
Numero MDL:
Codice UNSPSC:
12171500
ID PubChem:
NACRES:
NA.47

Forma fisica

solution

Livello qualitativo

Impiego in reazioni chimiche

reagent type: oxidant

Concentrazione

4% in H2O

tecniche

electron microscopy: suitable

Colore

colorless to yellow

pH

6.0-8.0

Densità

1.0 g/mL at 20 °C

applicazioni

hematology
histology

Temperatura di conservazione

2-8°C

Stringa SMILE

O=[Os](=O)(=O)=O

InChI

1S/4O.Os
VUVGYHUDAICLFK-UHFFFAOYSA-N

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Applicazioni

Osmium tetroxide solution has been used as a fixative in scanning and transmission electron microscopy.

Azioni biochim/fisiol

Osmium tetroxide is also referred to as osmium and is mainly used as a secondary fixative of tissues. The molecule reacts with lipid moieties and is responsible for the oxidation of unsaturated bonds of fatty acids. This reaction adds density and contrast to biological samples. In normal tissues, presence of osmium results in intense black staining which can be viewed by normal eye. In addition, it can be used as a mordant (a molecule which combines with stain or dye at later stages) in electron microscopy, thereby enhancing lead staining.

Confezionamento

5 mL in ampule
10 mL in ampule

Altre note

Due to the hazardous nature of osmium tetroxide, it is recommended to use an ampule opener when using this chemical.

Pittogrammi

CorrosionSkull and crossbones

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 2 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2

Codice della classe di stoccaggio

6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


Certificati d'analisi (COA)

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