G6257
Glutaraldeide
Grade II, 25% in H2O
Sinonimo/i:
Dialdeide glutarica, Pentano-1,5-diale
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About This Item
Formula condensata:
OHC(CH2)3CHO
Numero CAS:
Peso molecolare:
100.12
Beilstein:
605390
Numero MDL:
Codice UNSPSC:
12352114
ID PubChem:
NACRES:
NA.21
Prodotti consigliati
Tipo
Grade II
Livello qualitativo
Forma fisica
liquid
Concentrazione
25% in H2O
tecniche
electron microscopy: suitable
Colore
colorless
Intervallo di pH utile
2.9
Punto di fusione
-10 °C ((14 °F ))
Solubilità
water: soluble
applicazioni
cell analysis
sample preparation
Stringa SMILE
[H]C(CCCC([H])=O)=O
InChI
1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2
SXRSQZLOMIGNAQ-UHFFFAOYSA-N
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Descrizione generale
Glutaraldehyde, known as Glutaric dialdehyde or Pentane-1,5-dial, serves as a versatile reagent with applications spanning various research domains, including cell biology and biochemical research. It finds applications as a protein crosslinker, aids in enzyme immobilization for microscopy, and contributes to histochemistry and cytochemistry processes. As an amine-reactive homobifunctional crosslinker, it acts as a cell fixative before procedures like SDS-PAGE, staining, or electron microscopy, making it a valuable tool for diverse morphological studies.
Glutaraldehyde demonstrates efficacy in crosslinking amine and hydrazine derivatives to proteins and other amine-containing polymers. Notably, it allows direct coupling of biotin hydrazides to nucleic acids, offering potential applications in conjugating fluorescent hydrazides and hydroxylamines to DNA. Moreover, in histology studies, Glutaraldehyde is employed for preserving tissue sections and preparing them for detailed examination.
Glutaraldehyde demonstrates efficacy in crosslinking amine and hydrazine derivatives to proteins and other amine-containing polymers. Notably, it allows direct coupling of biotin hydrazides to nucleic acids, offering potential applications in conjugating fluorescent hydrazides and hydroxylamines to DNA. Moreover, in histology studies, Glutaraldehyde is employed for preserving tissue sections and preparing them for detailed examination.
Applicazioni
Glutaraldehyde solution has been used:
- for fixation of mouse and esophageal cancer cell lines
- to crosslink amyloid-β protein
- to crosslink gelatin in 3D scaffold preparation of trachea
Azioni biochim/fisiol
Glutaraldehyde is an effective protein crosslinker and finds application in techniques like enzyme immobilisation microscopy, histochemistry and cytochemistry. It exists in different forms under acidic or neutral conditions. It is toxic to aquatic organisms. Its allergic nature leads to hypersensitivity reactions. Contact of glutaraldehyde vapors in endoscopy contributes to Colitis.
Caratteristiche e vantaggi
- Versatile and adaptable for wide variety of research applications
- Ready-made solution reduces the need for preparation time
Confezionamento
Not refrigerated en route
Avvertenza
This grade is not recommended for use as an electron microscopy fixative.
Nota sulla preparazione
Not specially purified.
Altre note
For additional information on our range of Biochemicals, please complete this form.
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Esclusione di responsabilità
“The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.”
Prodotto comparabile
N° Catalogo
Descrizione
Determinazione del prezzo
Avvertenze
Danger
Indicazioni di pericolo
Classi di pericolo
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
Organi bersaglio
Respiratory system
Rischi supp
Codice della classe di stoccaggio
8A - Combustible corrosive hazardous materials
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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I clienti hanno visto anche
Chemical colitis due to glutaraldehyde: case series and review of the literature
Ahishali E, et al.
Digestive Diseases and Sciences, 54(12), 2541-2541 (2009)
Neutral red uptake assay for the estimation of cell viability/cytotoxicity
Repetto G, et al.
Nature Protocols, 3(7), 1125-1125 (2008)
Initiation of apoptosis, cell cycle arrest and autophagy of esophageal cancer cells by dihydroartemisinin
Du XX, et al.
Biomedicine and Pharmacotherapy, 67(5), 417-424 (2013)
Sorption characteristics of mixed molecules of glutaraldehyde from water on mesoporous acid-amine modified low-cost activated carbon: mechanism, isotherm, and kinetics
Lloyd M, et al.
Journal of Chemistry, 2015, 790-802 (2015)
A novel tissue-engineered trachea with a mechanical behavior similar to native trachea
Park JH, et al.
Biomaterials, 62(1), 106-115 (2015)
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