201030

Osmium tetroxide

ReagentPlus^®, 99.8%

• Sinonimo/i: Osmium(VIII)-oxide, ‘Osmic acid’
• Formula condensata: OsO₄
• Numero CAS: 20816-12-0
• Peso molecolare: 254.23
• Numero CE: 244-058-7
• Numero MDL: MFCD00011150
• Codice UNSPSC: 12352303
• ID PubChem: 329751973
• NACRES: NA.55

Proprietà

• Grado: reagent
• Densità del vapore: 8.8 (vs air)
• Tensione di vapore: 7 mmHg ( 20 °C)
• Nome Commerciale: ReagentPlus^®
• Saggio: 99.8%
• Stato: crystalline; powder
• Impiego in reazioni chimiche: reagent type: oxidant
• P. ebollizione: 130 °C (lit.)
• Punto di fusione: 39.5-41 °C (lit.)
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: O=[Os](=O)(=O)=O
• InChI: 1S/4O.Os; VUVGYHUDAICLFK-UHFFFAOYSA-N

Descrizione

Descrizione generale

Osmium tetroxide (OsO₄) is widely employed as a catalyst in various organic reactions. Stereochemical aspects of the OsO₄ assisted oxidation of allylic alcohols and their derivatives have been reported. Its reaction with olefins has been investigated. It participates as a catalyst for oxidizing fluoroquinolones, via reaction with potassium hexacyanoferrate(III) in alkaline medium. Kinetics of this oxidation reaction was studied.

Applicazioni

Osmium tetroxide may be employed as a catalyst for the hydroxylation of sterically hindered olefins.

Osmium tetroxide may be used in the following processes:

• To promote the lactonization of alkenols to lactones.
• To mediate the selective oxidative cleavage of olefins by oxone to form the corresponding ketones or carboxylic acids.
• Dihydroxylation of mono-trans-di, and trisubstituted olefins to form 1,2-diols with high enantioselectivity in the presence of chiral amines.

Widely used oxidizer for visualizing cells in microscopy. Promotes oxidative cleavage of graphene layers in carbon nanotubes creating the possibility of opening ′windows′ in fullerene cages.

Note legali

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS05
• Avvertenze: Danger
• Indicazioni di pericolo: H300 + H310 + H330,H314
• Consigli di prudenza: P260 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B
• Codice della classe di stoccaggio: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable