A-916

7-Aminoclonazepam solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Formula empirica (notazione di Hill): C₁₅H₁₂ClN₃O
• Numero CAS: 4959-17-5
• Peso molecolare: 285.73
• Numero MDL: MFCD00798467
• Codice UNSPSC: 41116107
• ID PubChem: 329771039
• NACRES: NA.24

Proprietà

• Grado: certified reference material
• Forma fisica: liquid
• Caratteristiche: SNAP-N-SPIKE^®, SNAP-N-SHOOT^®
• Confezionamento: ampule of 1 mL
• Produttore/marchio commerciale: Cerilliant^®
• Concentrazione: 1.0 mg/mL in acetonitrile
• tecniche: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• applicazioni: clinical testing
• Formato: single component solution
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: NC1=CC=C2C(C(C3=C(Cl)C=CC=C3)=NCC(N2)=O)=C1
• InChI: 1S/C15H12ClN3O/c16-12-4-2-1-3-10(12)15-11-7-9(17)5-6-13(11)19-14(20)8-18-15/h1-7H,8,17H2,(H,19,20); HEFRPWRJTGLSSV-UHFFFAOYSA-N

Descrizione

Descrizione generale

This certified Snap-N-Spike^® solution is suitable for use as a starting material in calibrators and controls for numerous GC/MS or LC/MS applications in forensic analysis, clinical toxicology and urine drug testing. As a major metabolite, 7-aminoclonazepam may be used to monitor use of the parent drug, clonazepam. Clonazepam, marketed as Klonopin^® and Rivotril, is a long-acting benzodiazepine with anxiolytic, anticonvulsant, muscle relaxant, and hypnotic properties.

Applicazioni

• 7-Aminoclonazepam as a Reference Standard in Forensic Toxicology: This benzodiazepine metabolite is critical for forensic applications, where it serves as a reference standard for the confirmation and quantitation of clonazepam in biological samples. Its reliable detection in toxicological screenings is crucial for legal and medical interpretations (Elenstål et al., 2023).


• Pharmacokinetic Studies with 7-Aminoclonazepam: In pharmacokinetics, 7-Aminoclonazepam is studied to understand the metabolic pathways of clonazepam, particularly its transformation and elimination in the human body. This research is vital for developing dosing regimens that optimize therapeutic outcomes while minimizing side effects (Øiestad et al., 2023).


• Stability Studies of 7-Aminoclonazepam: Stability testing of 7-Aminoclonazepam in various storage conditions provides essential data on how storage conditions affect the integrity of this compound. Such information ensures the accuracy and reliability of bioanalytical assays used in clinical and forensic settings (Dahlin & Petrides, 2022).

Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Klonopin is a registered trademark of Hoffmann-La Roche Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H225,H302 + H312 + H332,H319
• Consigli di prudenza: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Codice della classe di stoccaggio: 3 - Flammable liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): 35.6 °F - closed cup
• Punto d’infiammabilità (°C): 2 °C - closed cup