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36799

Sigma-Aldrich

7-(Diethylamino)coumarin-3-carboxylic acid

BioReagent, suitable for fluorescence, ≥98.0% (HPCE)

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About This Item

Formula empirica (notazione di Hill):
C14H15NO4
Numero CAS:
50995-74-9
Peso molecolare:
261.27
Beilstein:
6145963
Numero MDL:
MFCD00068721
Codice UNSPSC:
12352106
ID PubChem:
57649663
NACRES:
NA.32

Nome Commerciale

BioReagent

Livello qualitativo

200

Saggio

≥98.0% (HPCE)

Punto di fusione

222-224 °C (dec.) (lit.)

Solubilità

DMF: soluble
DMSO: soluble

Fluorescenza

λex 409 nm; λem 473 nm in 0.1 M Tris pH 9.0

Compatibilità

suitable for fluorescence

Stringa SMILE

CCN(CC)c1ccc2C=C(C(O)=O)C(=O)Oc2c1

InChI

1S/C14H15NO4/c1-3-15(4-2)10-6-5-9-7-11(13(16)17)14(18)19-12(9)8-10/h5-8H,3-4H2,1-2H3,(H,16,17)
WHCPTFFIERCDSB-UHFFFAOYSA-N

Applicazioni

7-(Diethylamino)coumarin-3-carboxylic acid (7-DCCA) may be used to study its photophysical properties in various solvents and solvent mixtures and as a fluorescent label for amine modification and protein conjugation

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Altre note

Fluorescent label for amine modification and protein conjugation

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
BCBX5579
BCBS9724V
BCBP8716V
BCBK9205V
BCBJ2043V

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Sigma-Aldrich

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Alicia S Kriete et al.
Interface focus, 9(4), 20190013-20190013 (2019-07-03)
Urinary incontinence is a significant challenge for women who are affected by it. We propose augmenting the tissue structure to restore normal biomechanics by molecularly engineering the tissue using a novel family of biomimetic proteoglycans (BPGs). This work examines the
Simone Kunzelmann et al.
Biochemistry, 49(5), 843-852 (2009-12-24)
A single-stranded DNA binding protein (SSB), labeled with a fluorophore, interacts with single-stranded DNA (ssDNA), giving a 6-fold increase in fluorescence. The labeled protein is the adduct of the G26C mutant of the homotetrameric SSB from Escherichia coli and a
J R Leisey et al.
The American journal of physiology, 267(2 Pt 2), H645-H653 (1994-08-11)
Quantitation of metabolic parameters using the technique of cardiac surface fluorescence is complicated by motion and changes in tissue absorption. Because ratio fluorescence methodology can be applied to eliminate motion-induced errors, in the current study, we used a ratio fluorescence
A Kakio et al.
The Journal of biological chemistry, 276(27), 24985-24990 (2001-05-09)
GM1 ganglioside-bound amyloid beta-protein (GM1/Abeta), found in brains exhibiting early pathological changes of Alzheimer's disease (AD) including diffuse plaques, has been suggested to be involved in the initiation of amyloid fibril formation in vivo by acting as a seed. To
Rosaria Notariale et al.
Acta biochimica Polonica, 65(4), 585-594 (2018-11-18)
The major acid-soluble protein components of the mussel Mytilus galloprovincialis sperm chromatin consist of the protamine-like proteins PL-II, PL-III and PL-IV, an intermediate group of sperm nuclear basic proteins between histones and protamines. The aim of this study was to
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