850103P

17:1 Lyso PI

1-(10Z-heptadecenoyl)-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder

• Sinonimo/i: PI(17:1(10Z)/0:0); 110718
• Formula empirica (notazione di Hill): C₂₆H₅₂NO₁₂P
• Numero CAS: 1246353-39-8
• Peso molecolare: 601.66
• Codice UNSPSC: 51191904
• NACRES: NA.25

Proprietà

• Saggio: >99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC)
• Stato: powder
• Confezionamento: pkg of 1 × 100 μg (with stopper and crimp cap (850103P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850103P-500ug))
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand 850103P
• Tipo di lipide: phosphoglycerides
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• Stringa SMILE: [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCCC/C=C\CCCCCC)=O.[NH4+]
• InChI: 1S/C26H49O12P.H3N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20(28)36-17-19(27)18-37-39(34,35)38-26-24(32)22(30)21(29)23(31)25(26)33;/h7-8,19,21-27,29-33H,2-6,9-18H2,1H3,(H,34,35);1H3/b8-7-;/t19-,21-,22-,23+,24-,25-,26-;/m1./s1; VFLBJIAFDLNWCY-SNLSZFGJSA-N

Descrizione

Descrizione generale

Lysophosphatidylinositol (LPI), a degradation product of phosphatidylinositol (PI) is a lysophospholipid subspecies, which carries inositol in its head group.

Applicazioni

17:1 Lyso PI (1-(10Z-heptadecenoyl)-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol)) has been used as an internal standard in LC-MS of mice brain lipidomic analysis. It may be used as internal standard in for the analysis of lysophosphatidylinositols (LPIs) in mice using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC/ESI-MS) and in the quantification of lysoPI (LPI) in livers of chronic high-fat diet (HFD)-fed WT and KO mice using liquid chromatography with tandem mass spectrometry (LC-MS-MS) system.

Azioni biochim/fisiol

Increased circulating levels of L-alpha-lysophosphatidylinositol (LPI) are associated with cancer and LPI is a potent ligand for the G-protein-coupled receptor GPR55.

Lysophosphatidylinositol (LPI) serve as a bioactive lysophospholipid mediator. It favors mitogenic activity in quiescent fibroblasts. LPI has the ability to block hippocampal neuronal death in conditions of forebrain ischemia.

Confezionamento

2 mL Amber Serum Vial with Stopper and Crimp Cap (850103P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850103P-500ug)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): No data available
• Punto d’infiammabilità (°C): No data available