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Documenti fondamentali

791644C

Avanti

18:1-d7 Lyso PE

Avanti Research™ - A Croda Brand 791644C

Sinonimo/i:

1-oleoyl(d7)-2-hydroxy-sn-glycero-3-phosphoethanolamine

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About This Item

Formula empirica (notazione di Hill):
C23H39D7NO7P
Numero CAS:
2260669-47-2
Peso molecolare:
486.63
Codice UNSPSC:
41141825
NACRES:
NA.25

Saggio

>99% (TLC)

Stato

liquid

Confezionamento

pkg of 1 × 1 mL (791644C-1mg)

Produttore/marchio commerciale

Avanti Research™ - A Croda Brand 791644C

Concentrazione

1 mg/mL (791644C-1mg)

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Categorie correlate

Descrizione generale

18:1-d7 Lyso PE (1-oleoyl(d7)-2-hydroxy-sn-glycero-3-phosphoethanolamine) is a deuterated phospholipid. The glycerol is esterified with oleic acid. Oleic acid harbors the deuterium ions. Lysophosphatidylethanolamine (LPE) is generated from phosphatidylethanolamine by the action of enzyme phospholipase A2.
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH™ LIPIDOMIX™ Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

Applicazioni

18:1-d7 Lyso PE (1-oleoyl(d7)-2-hydroxy-sn-glycero-3-phosphoethanolamine) has been used as a component of extraction solvent for lipid isolation from biological samples. It has also been used as an isotopically labeled lipid internal standard for correction of lipids detected in lipid droplets using shotgun mass spectrometry analysis.

Azioni biochim/fisiol

Lysophosphatidylethanolamine (LPE) plays a key role in neuronal differentiation in PC12 cells. It possesses antibacterial and antifungal activity. LPE also favour the calcium transport through G-protein-coupled receptor (GPCR).

Confezionamento

5 mL Clear Glass Sealed Ampule (791644C-1mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC

Comunemente ordinati con questo prodotto

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Organi bersaglio

Central nervous system, Liver,Kidney

Codice della classe di stoccaggio

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

does not flash

Punto d’infiammabilità (°C)

does not flash

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Caixia Ren et al.
Lipids in health and disease, 17(1), 22-22 (2018-02-06)
Migraine is a prevalent, disabling type of primary headache disorder associated with a high socioeconomic burden. The clinical management of migraine is challenging. This study was to identify potential serum lipidomic biomarkers of migraine. The serum lipidomic profile of migraine
Kumiko Makide et al.
Prostaglandins & other lipid mediators, 89(3-4), 135-139 (2009-05-12)
It is now widely accepted that lysophospholipids (LPLs), a product of the phospholipase A reaction, function as mediators through G-protein-coupled receptors. Notably, recent studies of lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) have revealed their essential roles in vivo. On
Chuchu Wang et al.
Nature communications, 11(1), 1531-1531 (2020-03-27)
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using

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